Detailed description page of B3Pdb


This page provides detail information of Selected ID b3pdb_0056
Primary information
B3PDB IDb3pdb_0056
Peptide NameAPep2
PEPTIDE SEQUENCE (1-letter)TFFYGGSRGKRNNFKTEEY
PEPTIDE SEQUENCE (3-letter)ThrPhePheTyrGlyGlySerArgGlyLysArgAsnAsnPheLysThrGluGluTyr
N-terminal modificationFAM is conjgated at the N-terminal
C-terminal modificationNA
Chemical modificationNA
Peptide Length19
ConformationLinear
Peptide NatureNA
Source/Origin of peptideChemically synthesized
SMILESN[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)O
Cell LinebEnd.3 cells
In vitro CONCENTRATIONNA
In vitro METHODImmunofluorescence microscopy
In vitro RESULTIt shows the permeability towards the BBB.
ANIMAL MODELNA
In vivo CONCENTRATIONNA
In vivo MODE OF DELIVERYNA
In vivo METHODNA
In vivo RESULTNA
ACTIONThese novel peptide conjugates have the capacity to act as promising brain shuttles
TRANSPORT TYPEReceptor-mediated transcytosis
SUBCELLULAR LOCALISATIONNA
COMBINATIONCombined
PHYSICAL CONDITIONNA
RESPONSENA
RESULTNA
LABELNA
PMID32055384