Detailed description page of B3Pdb


This page provides detail information of Selected ID b3pdb_0041
Primary information
B3PDB IDb3pdb_0041
Peptide NameOdorranalectin
PEPTIDE SEQUENCE (1-letter)YASPKSFRYPNGVLACT
PEPTIDE SEQUENCE (3-letter)TyrAlaSerProLysSerPheArgTyrProAsnGlyValLeuAlaCysThr
N-terminal modificationNA
C-terminal modificationNA
Chemical modificationConjugated with 5(6)-carboxyfluorescein at N-termi
Peptide Length17
ConformationLinear
Peptide NatureNA
Source/Origin of peptidefrog
SMILESN[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CO)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(=O)N)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)O
Cell LinehCMEC/D3 cells
In vitro CONCENTRATION2500 cells per cm square
In vitro METHODLC/MS and Fluorescence microscopy
In vitro RESULTIt shows the cellulr uptake of OL at the BBB endothelium.
ANIMAL MODELNA
In vivo CONCENTRATIONNA
In vivo MODE OF DELIVERYNA
In vivo METHODNA
In vivo RESULTNA
ACTIONTAT-Modified MVIIA for Crossing the Blood-Brain Barrier
TRANSPORT TYPEReceptor-mediated transcytosis
SUBCELLULAR LOCALISATIONNA
COMBINATIONAlone
PHYSICAL CONDITIONNA
RESPONSENA
RESULTNA
LABELNA
PMID31068126