Detailed description page of B3Pdb


This page provides detail information of Selected ID b3pdb_0040
Primary information
B3PDB IDb3pdb_0040
Peptide NameAEP-dendron
PEPTIDE SEQUENCE (1-letter)LRKLRKRLLR
PEPTIDE SEQUENCE (3-letter)LeuArgLysLeuArgLysArgLeuLeuArg
N-terminal modificationAEP attached at N-terminal
C-terminal modificationNA
Chemical modificationNA
Peptide Length10
ConformationLinear
Peptide NatureCationic
Source/Origin of peptideApoE protein
SMILESN[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O
Cell LinebEnd.3 Cell Line
In vitro CONCENTRATION50000 cells per cm square
In vitro METHODLaser Scanning Confocal Microscopy (LSCM)
In vitro RESULTLSCM showed the cellular uptake of the RMT-competent AEP-dendron.
ANIMAL MODELNA
In vivo CONCENTRATIONNA
In vivo MODE OF DELIVERYNA
In vivo METHODNA
In vivo RESULTNA
ACTIONSuccessful synthesis of dendronised carrier systems with the potential to act as carriers for improv
TRANSPORT TYPEReceptor-mediated transcytosis
SUBCELLULAR LOCALISATIONNA
COMBINATIONComined
PHYSICAL CONDITIONNA
RESPONSENA
RESULTNA
LABELNA
PMID30972332