Detailed description page of B3Pdb
This page provides detail information of Selected ID b3pdb_0006 |
| Primary information | |
|---|---|
| B3PDB ID | b3pdb_0006 |
| Peptide Name | NR2B9c |
| PEPTIDE SEQUENCE (1-letter) | KLSSIESDV |
| PEPTIDE SEQUENCE (3-letter) | LysLeuSerSerIleGluSerAspVal |
| N-terminal modification | NA |
| C-terminal modification | NA |
| Chemical modification | NA |
| Peptide Length | 9 |
| Conformation | NA |
| Peptide Nature | NA |
| Source/Origin of peptide | NA |
| SMILES | N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(C(C)C)C(=O)O |
| Cell Line | NA |
| In vitro CONCENTRATION | NA |
| In vitro METHOD | NA |
| In vitro RESULT | NA |
| ANIMAL MODEL | Rat |
| In vivo CONCENTRATION | NA |
| In vivo MODE OF DELIVERY | Intranasal |
| In vivo METHOD | HPLC-MS/MS |
| In vivo RESULT | NR2B9c-WGA-NPs are able to bypass the BBB and effectively transport NR2B9c into the brain and neuron |
| ACTION | It can protect neurons against excitotoxicity, reduce ischemic brain injury and ameliorate neurologi |
| TRANSPORT TYPE | transcytosis |
| SUBCELLULAR LOCALISATION | NA |
| COMBINATION | NR2B9c is combined with WGA-modified nanoparticles |
| PHYSICAL CONDITION | ischemic stroke |
| RESPONSE | NA |
| RESULT | NA |
| LABEL | NA |
| PMID | 30428334 |