Browse result page of B3Pdb

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B3pdbID	PEPTIDE NAME	PEPTIDE SEQUENCE (1-letter)	PEPTIDE SEQUENCE (3-letter)	N-TERMINAL MODIFICATION	C-TERMINAL MODIFICATION	CHEMICAL MODIFICATION	PEPTIDE LENGTH	PEPTIDE CONFORMATION	PEPTIDE NATURE	SOURCE/ORIGIN OF PEPTIDE	SMILES	CELL LINE	In vitro CONCENTRATION	In vitro METHOD	In vitro RESULT	ANIMAL MODEL	In vivo CONCENTRATION	In vivo MODE OF DELIVERY	In vivo METHOD	In vivo RESULT	ACTION	TRANSPORT TYPE	SUBCELLULAR LOCALISATION	COMBINATION	PHYSICAL CONDITION	RESPONSE	RESULT	LABEL	PMID
B3pdbIDb3pdb_0066	PEPTIDE NAMEHAVN1	PEPTIDE SEQUENCE (1-letter)SHAVSS	PEPTIDE SEQUENCE (3-letter)SerHisAlaValSerSer	N-TERMINAL MODIFICATIONNA	C-TERMINAL MODIFICATION NA	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH6	PEPTIDE CONFORMATIONCyclic	PEPTIDE NATURENA	SOURCE/ORIGIN OF PEPTIDEChemically synthesized	SMILESN[C@@]([H])(CO)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CO)C(=O)O	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATIONNA	In vivo MODE OF DELIVERYIntracerebral ventricular	In vivo METHODMass Spectromtery	In vivo RESULTIt is able to deliver an IRdye800CW-labeled IgG monoclonal antibody into the brain.	ACTIONSynthesized novel cyclic peptides are able efectively modulate the BBB to enhance the delivery of mA	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONCombined with monoclonal antibody	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 31683745
B3pdbIDb3pdb_0067	PEPTIDE NAMEHAVN2	PEPTIDE SEQUENCE (1-letter)SHAVS	PEPTIDE SEQUENCE (3-letter)SerHisAlaValSer	N-TERMINAL MODIFICATIONNA	C-TERMINAL MODIFICATION NA	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH5	PEPTIDE CONFORMATIONCyclic	PEPTIDE NATURENA	SOURCE/ORIGIN OF PEPTIDEChemically synthesized	SMILESN[C@@]([H])(CO)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CO)C(=O)O	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATIONNA	In vivo MODE OF DELIVERYIntracerebral ventricular	In vivo METHODMass Spectromtery	In vivo RESULTIt is able to deliver an IRdye800CW-labeled IgG monoclonal antibody into the brain.	ACTIONSynthesized novel cyclic peptides are able efectively modulate the BBB to enhance the delivery of mA	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONCombined with monoclonal antibody	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 31683745
B3pdbIDb3pdb_0068	PEPTIDE NAMELinear ADTHAV	PEPTIDE SEQUENCE (1-letter)TPPVSHAV	PEPTIDE SEQUENCE (3-letter)ThrProProValSerHisAlaVal	N-TERMINAL MODIFICATIONAcetylaed at N-terminal	C-TERMINAL MODIFICATION Amide group is attached at C-terminal	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH8	PEPTIDE CONFORMATIONLinear	PEPTIDE NATURENA	SOURCE/ORIGIN OF PEPTIDEChemically synthesized	SMILESN[C@@]([H])([C@]([H])(O)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)O	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATIONNA	In vivo MODE OF DELIVERYIntracerebral ventricular	In vivo METHODMass Spectromtery	In vivo RESULTIt is able to deliver an IRdye800CW-labeled IgG monoclonal antibody into the brain.	ACTIONSynthesized novel cyclic peptides are able efectively modulate the BBB to enhance the delivery of mA	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONCombined with monoclonal antibody	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 31683745
B3pdbIDb3pdb_0069	PEPTIDE NAMECyclic ADTHAV	PEPTIDE SEQUENCE (1-letter)TPPVSHAV	PEPTIDE SEQUENCE (3-letter)ThrProProValSerHisAlaVal	N-TERMINAL MODIFICATIONNA	C-TERMINAL MODIFICATION NA	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH8	PEPTIDE CONFORMATIONCyclic	PEPTIDE NATURENA	SOURCE/ORIGIN OF PEPTIDEChemically synthesized	SMILESN[C@@]([H])([C@]([H])(O)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)O	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATIONNA	In vivo MODE OF DELIVERYIntracerebral ventricular	In vivo METHODMass Spectromtery	In vivo RESULTIt is able to deliver an IRdye800CW-labeled IgG monoclonal antibody into the brain.	ACTIONSynthesized novel cyclic peptides are able efectively modulate the BBB to enhance the delivery of mA	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONCombined with monoclonal antibody	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 31683745
B3pdbIDb3pdb_0070	PEPTIDE NAMEADTC5	PEPTIDE SEQUENCE (1-letter)CDTPPVC	PEPTIDE SEQUENCE (3-letter)CysAspThrProProValCys	N-TERMINAL MODIFICATIONNA	C-TERMINAL MODIFICATION Amide group is attached at C-terminal	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH7	PEPTIDE CONFORMATIONCyclic	PEPTIDE NATURENA	SOURCE/ORIGIN OF PEPTIDEChemically synthesized	SMILESN[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CS)C(=O)O	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATIONNA	In vivo MODE OF DELIVERYIntracerebral ventricular	In vivo METHODMass Spectromtery	In vivo RESULTIt is able to deliver an IRdye800CW-labeled IgG monoclonal antibody into the brain.	ACTIONSynthesized novel cyclic peptides are able efectively modulate the BBB to enhance the delivery of mA	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONCombined with monoclonal antibody	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 31683745