Browse result page of B3Pdb

The total number entries retrieved from this search are 65, scroll left/right for detailed information.

B3pdbID	PEPTIDE NAME	PEPTIDE SEQUENCE (1-letter)	PEPTIDE SEQUENCE (3-letter)	N-TERMINAL MODIFICATION	C-TERMINAL MODIFICATION	CHEMICAL MODIFICATION	PEPTIDE LENGTH	PEPTIDE CONFORMATION	PEPTIDE NATURE	SOURCE/ORIGIN OF PEPTIDE	SMILES	CELL LINE	In vitro CONCENTRATION	In vitro METHOD	In vitro RESULT	ANIMAL MODEL	In vivo CONCENTRATION	In vivo MODE OF DELIVERY	In vivo METHOD	In vivo RESULT	ACTION	TRANSPORT TYPE	SUBCELLULAR LOCALISATION	COMBINATION	PHYSICAL CONDITION	RESPONSE	RESULT	LABEL	PMID
b3pdb_0973	Doxorubicin-(D)-SynB	Doxorubicin-linker-rrlsysrrrf	Doxorubicin-linker-(D)Arg-(D)Arg-(D)Leu-(D)Ser-(D)Tyr-(D)Ser-(D)Arg-(D)Arg-(D)Arg-(D)Phe			NA	10	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	Permeability	NA	NA	NA	Volume of donor compartment	0.9618 ml/g	H3/C14	11123372
b3pdb_0974	SynB3	RRLSYSRRRF-NH2	Arg-Arg-Leu-Ser-Tyr-Ser-Arg-Arg-Arg-Phe-NH2			NA	10	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	Permeability	NA	NA	NA	Volume of donor compartment	0.7884 ml/g	H3/C14	11123372
b3pdb_1018	Arginine vasopressin	CYFQNCPRG	Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly	NA	NA	Cys1-Cys6	9	Linear	NA	Chemically synthesized	C1C[C@H](N(C1)C(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	Permeability	NA	NA	NA	Unidirectional flux rate constant	0.00237 mL/(g x min)	H3/C14	1422832
b3pdb_1019	Arginine vasopressin	CYFQNCPRG	Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly	NA	NA	Cys1-Cys6	9	Linear	NA	Chemically synthesized	C1C[C@H](N(C1)C(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	Permeability	NA	NA	NA	Initial distribution vaolume	0.0042 ml/g	H3/C14	1422832
b3pdb_1034	N-Tyr-MIF-1	YPLG-NH2	Tyr-Pro-Leu-Gly-NH2	NA	NA	NA	4	Linear	NA	NA	CCCC[C@@H](C(=O)NCC(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC2=CC=C(C=C2)O)N	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	non saturable	NA	NA	NA	Unidirectional flux rate constant	0.004444 mL/(g x min)	Direct iodination	2575441
b3pdb_1059	PEG-D-Penicillamine-	mPEG-Y-pen-GF-pen	mPEG-Tyr-(D)Pen-Gly-Phe-D(Pen)	NA	NA	pen2-pen5	NA	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	In situ perfusion (single time)	NA	NA	NA	saturable	NA	NA	NA	in vitro influx rate	3.41%	Direct iodination	11454951
b3pdb_1086	Insulin detemir, Lev	A-chain:GIVEQCCTSICSLYQLENYCN B-chain: FVNQHLCGSHLVEALYLVCGERGFFYTPK-myristic acid	A-chain: Gly-Ile-Val-Glu-Gln-Cys-Cys-Thr-Ser-Ile-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn B-chain:Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-myristic acid	NA	NA	CysA6-CysA11; CysA7-CysB7; CysA20-CysB19	50	Linear	NA	Chemically synthesized	CCCCCCCCCCCCCC(=O)NCCCC[C@@H](C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H]5CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]6CSSC[C@@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N5)C(C)C)CC(C)C)CC7=CC=C(C=C7)O)CC(C)C)C)CCC(=O)O)C(C)C)CC(C)C)CC8=CN=CN8)CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC9=CN=CN9)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC1=CC=CC=C1)N)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N6)[C@@H](C)CC)CO)[C@@H](C)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)CN)CO)CC(C)C)CC1=CC=C(C=C1)O)CCC(=O)N)CC(C)C)CCC(=O)O)CC(=O)N)CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC(=O)N)C(=O)O	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	Permeability	NA	NA	NA	Unidirectional flux rate constant	0 mL/(g x min)	Direct iodination	25492620
b3pdb_1088	Ziconotide, SNX-111,	CKGKGAKCSRLMYDCCTGSCRSGKC	Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys	NA	NA	Cys1-Cys16; Cys8-Cys20; Cys15-Cys25	25	Linear	NA	Chemically synthesized	C[C@H]1C(=O)N[C@H](C(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N1)CCCCN)CCCCN)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N3)CO)[C@@H](C)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)CO)CCCNC(=N)N)CC(C)C)CCSC)CC4=CC=C(C=C4)O)CC(=O)O)C(=O)N)CCCCN)CO)CCCNC(=N)N)CCCCN	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	Permeability	NA	NA	NA	Unidirectional flux rate constant	0.0042 mL/(g x min)	Direct iodination	10822104
b3pdb_1089	Ziconotide, SNX-111,	CKGKGAKCSRLMYDCCTGSCRSGKC	Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys	NA	NA	Cys1-Cys16; Cys8-Cys20; Cys15-Cys25	25	Linear	NA	Chemically synthesized	C[C@H]1C(=O)N[C@H](C(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N1)CCCCN)CCCCN)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N3)CO)[C@@H](C)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)CO)CCCNC(=N)N)CC(C)C)CCSC)CC4=CC=C(C=C4)O)CC(=O)O)C(=O)N)CCCCN)CO)CCCNC(=N)N)CCCCN	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	Permeability	NA	NA	NA	Initial distribution vaolume	0.0018 ml/g	Direct iodination	10822104
b3pdb_1099	ANG4043, Angiopep2-a	NA	NA	NA	NA	NA	NA	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	saturable	NA	NA	NA	Unidirectional flux rate constant	0.096 mL/(g x min)	Direct iodination	25492620
b3pdb_1176	L57	TWPKHFDKHTFYSILKLGKH	Thr-Trp-Pro-Lys-His-Phe-Asp-Lys-His-Thr-Phe-Tyr-Ser-Ile-Leu-Lys-Leu-Gly-Lys-His	NA	NA	NA	20	Linear	NA	Hemoglobin	NA	NA	NA	NA	NA	NA	NA	In situ perfusion (single time)	NA	NA	NA	Permeability	NA	NA	NA	% injected dose	0.22 %/g	Direct iodination	29090274
b3pdb_1191	Gly-Pro	GP	Gly-Pro	NA	NA	NA	2	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	Permeability	NA	NA	NA	Unidirectional flux rate constant	0.00349 mL/(g x min)	NA	30962462
b3pdb_1192	Gly-Pro	GP	Gly-Pro	NA	NA	NA	2	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	Permeability	NA	NA	NA	Brain/perfusate ratio	10.9	NA	30962462
b3pdb_1193	Tyr-Pro	TP	Tyr-Pro	NA	NA	NA	2	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	Permeability	NA	NA	NA	Unidirectional flux rate constant	0.00353 mL/(g x min)	NA	30962462
b3pdb_1194	Tyr-Pro	TP	Tyr-Pro	NA	NA	NA	2	Linear	NA	Chemically synthesized	NA	NA	NA	NA	NA	NA	NA	in situ brain perfusion	NA	NA	NA	Permeability	NA	NA	NA	Brain/perfusate ratio	10.5	NA	30962462