Browse result page of AntiTbPdb
The total number entries retrieved from this search are 547
| ID | Name | Sequence | N-Terminal Modification | C-Terminal Modification | Chemical Modification | Linear/Cyclic | Length | Chirality | Nature | Source | Origin | Species | Strain | Inhibition Concentration | In vitro/ In vivo | Cell Line | Intracellular Inhibition | Cytotoxicity | Animal Model | Effective Dose in model organism | Immune Responce | Mechanism of Action | Target | Combination Therapy | Other Activities | Year of Publication | Pubmed ID/ Patent No. |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| antitb_1680 | 61-26 | not available | NA | NA | None | NA | 0 | NA | Weakly basic | Natural | Bacillus, strain 61-26, | Mycobacterium Tuberculosis | Mycobacterium tuberculosis H37Rv | MIC = >50 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Antibacterial against Bacillus subtilis PCI 219, Bacillus anthracis, Staphylococcus aureus FDA 209P JC-1, Staphylococcus aureus Smith, Diplococcus pneumoniae type I, Streptococcus pyogenes C-203, Escherichia coli NIHJ JC-2, Klebsiella pneumoniae, Salmonella typhimurium And Antifungal against Candida albicans M-9, Trichophyton rubrum, Trichophyton mentagrophytes | 1974 | 1112765 |
| antitb_1681 | KM-8 | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptoverticillium | M. smegmatis | Mycobacterium smegmatis ATCC 607 | MIC = 100 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Antibacterial against Staphylococcus aureus FDA 209 P, Sarcina lutea PCI 1001, Bacillus subtilis PCI 219, Bacillus cereus var. mycoides, Bacillus agri, Bacillus anthracis, Corynebacterium paurometabolurn, Escherichia coli NIHJ, Klebsiella pneumoniae PCI 602, Shigella flexneri, Xanthomonas oryzae Antifungal Candida albicans, Aspergillus niger, Alternaria kikuchiana, Botrytis cinerea | 1975 | 1184471 |
| antitb_1682 | Cryomycin | not available | NA | NA | None | NA | 0 | NA | Weakly acidic | Natural | Streptomyces griseus subsp. psychrophilus, | Mycobacterium avium | Mycobacterium avium IFO 3 | MIC = 20 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Antibacterial against bacillus megaterium, E.coli, P.aeuroginosaand S.aureus,Antifungal Aspergillus niger, Mucor racemosus , Penicillium chrysogenum, Neurospora crassa | 1972 | 4630599 |
| antitb_1683 | S35-Siomycin | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces sioyaensis | Mycobacterium tuberculosis | Mycobacterium tuberculosis | NA | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | many clinical resistant strains of Staphylococcus | 1972 | 4630599 |
| antitb_1684 | Jolipeptin | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Bacillus polymyxa var. colistinus Koyama | Mycobacterium Tuberculosis | Mycobacterium tuberculosis 607 | MIC = 10 μg/mL | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Antibacterial against E. coli B, E. coli NIHJ, Staphylococcus aureus FDA 209P, Bacillus subtilis PCI 219, Micrococcus lysodeihticus | 1972 | 5042449 |
| antitb_1685 | S-520 | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces diastaticus | Mycobacterium Tuberculosis | Mycobacterium tuberculosis 607 | MIC = 100 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Antibacterial against Bacillus subtilis, Bacillus anthracis, Staphylococcus aureus, Staphylococcus aureus,Streptococcus pyogenes,Diplococcus pneumoniae, Sarcinalutea Corynebacterium diphtheriae | 1970 | 5459623 |
| antitb_1686 | S-520 | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces diastaticus | Mycobacterium smegmatis | Mycobacterium smegmatis | MIC = 10 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Antibacterial against Bacillus subtilis, Bacillus anthracis, Staphylococcus aureus, Staphylococcus aureus,Streptococcus pyogenes,Diplococcus pneumoniae, Sarcinalutea Corynebacterium diphtheriae | 1970 | 5459623 |
| antitb_1687 | S-520 | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces diastaticus | Mycobacterium phlei | Mycobacterium phlei | MIC = 5 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Antibacterial against Bacillus subtilis, Bacillus anthracis, Staphylococcus aureus, Staphylococcus aureus,Streptococcus pyogenes,Diplococcus pneumoniae, Sarcinalutea Corynebacterium diphtheriae | 1970 | 5459623 |
| antitb_1688 | Pepthiomycin A | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces roseospinusx | Mycobacterium | Mycobacterium 607 | MIC = >100 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Antibacterial against Staphylococus aureus,arcina ltea etc Antifungal against Aspergillus niger | 1968 | 5723086 |
| antitb_1689 | Pepthiomycin B | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces roseospinusx | Mycobacterium | Mycobacterium 607 | MIC = >50 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Antibacterial against Staphylococus aureus,arcina ltea etc Antifungal against Aspergillus niger | 1968 | 5723086 |
| antitb_1690 | Myxovalargins | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Myxobacterium Myxococcus fulvus strain Mx f65. | Mycobacterium | Mycobacterium phlei | NA | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Antibacterial against Corynebacterium mediolanum, Bacillus megaterium, Bacillus subtilis, Staphylococcus aureus, Brevibacterium ammoniagenes, Arthrobacter simplex, Arthrobacter rubellus, Micrococcus lysodeikticus, Micrococcus luteus, Nocardia (lava), Nocardia corallina, Rhizobium 1-595, Rhizobium meliloti, Myxococcus fulvus Mx f65, Myxococcus fulvus Mx f65-M9, Salmonella typhimurium, Escherichia coli, Klebsiella sp., Serratia marcescens, Pseudomonas fluorescens,Pseudomonas aeruginosa, Pseudomona | 1982 | 6432761 |
| antitb_1691 | Takaokamycin | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces sp. AC-1978, | Mycobacterium smegmatis | Mycobacterium smegmatis ATCC 607 | MIC = >100 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Staphylococcus aureus ATCC 6538P, S. aureus FDA 209P, Bacillus subtilis ATCC 6633, B. cereus IFO 3001, Micrococcus luteus ATCC 9341, Escherichia coli NIHJ, E. coli NIHJ JC-2, Klebsiella pneumoniae ATCC 10031, Proteus vulgaris IFO 3167, Pseudomonas aeruginosa IFO 3080 | 1984 | 6732903 |
| antitb_1692 | Tuberactinamine N | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces griseoverticillatus var. tuberacticus | Mycobacterium smegmatis | Mycobacterium smegmatis ATCC 607 | MIC = 12.5 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Bactericidal against corneybacterium diptheriae, bacillus subtilis, E.coli, Salmonellatyphosa, klebsiella pneumoniare,proteus vulgaris | 1975 | 28292 |
| antitb_1693 | Tuberactinomycin N | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces griseoverticillatus var. tuberacticus | Mycobacterium smegmatis | Mycobacterium smegmatis ATCC 607 | MIC = 12.5 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Bactericidal against corneybacterium diptheriae, bacillus subtilis, E.coli, Salmonellatyphosa, klebsiella pneumoniare,proteus vulgaris | 1975 | 28292 |
| antitb_1694 | Tuberactinamine N | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces griseoverticillatus var. tuberacticus | Mycobacterium bovis | Mycobacterium bovis BCG | Reduction in CFU at 12.5 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Bactericidal against corneybacterium diptheriae, bacillus subtilis, E.coli, Salmonellatyphosa, klebsiella pneumoniare,proteus vulgaris | 1975 | 28292 |
| antitb_1695 | Tuberactinomycin N | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces griseoverticillatus var. tuberacticus | Mycobacterium bovis | Mycobacterium bovis BCG | Reduction in CFU 25μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Bactericidal against corneybacterium diptheriae, bacillus subtilis, E.coli, Salmonellatyphosa, klebsiella pneumoniare,proteus vulgaris | 1975 | 28292 |
| antitb_1696 | Tuberactinamine N | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces griseoverticillatus var. tuberacticus | Mycobacterium bovis | Mycobacterium bovis BCG | Reduction in CFU at 25 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Bactericidal against corneybacterium diptheriae, bacillus subtilis, E.coli, Salmonellatyphosa, klebsiella pneumoniare,proteus vulgaris | 1975 | 28292 |
| antitb_1697 | Tuberactinomycin N | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces griseoverticillatus var. tuberacticus | Mycobacterium bovis | Mycobacterium bovis BCG | Reduction in CFU at 50 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Bactericidal against corneybacterium diptheriae, bacillus subtilis, E.coli, Salmonellatyphosa, klebsiella pneumoniare,proteus vulgaris | 1975 | 28292 |
| antitb_1698 | Tuberactinamine N | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces griseoverticillatus var. tuberacticus | Mycobacterium bovis | Mycobacterium bovis BCG | MIC = 50 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Bactericidal against corneybacterium diptheriae, bacillus subtilis, E.coli, Salmonellatyphosa, klebsiella pneumoniare,proteus vulgaris | 1975 | 28292 |
| antitb_1699 | Tuberactinomycin N | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces griseoverticillatus var. tuberacticus | Mycobacterium bovis | Mycobacterium bovis BCG | MIC = 100 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Bactericidal against corneybacterium diptheriae, bacillus subtilis, E.coli, Salmonellatyphosa, klebsiella pneumoniare,proteus vulgaris | 1975 | 28292 |
| antitb_1700 | Tuberactinamine N | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces griseoverticillatus var. tuberacticus | Mycobacterium bovis | Mycobacterium bovis BCG | MIC = 100 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Bactericidal against corneybacterium diptheriae, bacillus subtilis, E.coli, Salmonellatyphosa, klebsiella pneumoniare,proteus vulgaris | 1975 | 28292 |
| antitb_1701 | Tuberactinamine N | not available | NA | NA | None | NA | 0 | NA | NA | Natural | Streptomyces griseoverticillatus var. tuberacticus | Mycobacterium bovis | Mycobacterium bovis BCG | MIC = 6.3 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Bactericidal against corneybacterium diptheriae, bacillus subtilis, E.coli, Salmonellatyphosa, klebsiella pneumoniare,proteus vulgaris | 1975 | 28292 |
| antitb_1723 | SEQ ID NO 3 | NVTSIHSLL | Free | Free | None | Linear | 9 | L | NA | Protein Derived | From the proetins containing mycobacterial CD8 T cell epitopes | Mycobacterium tuberculosis | Mycobacterium tuberculosis | NA | In vitro | PBMcs | NA | NA | β2-microglobulin gene knowckout mice, TAP-1 null mutant mice and HSP-65 immunized mice | NA | IFN-γ release increases | By CD8 T cell response | NA | None | None | 2002 | US 2002/013197 |
| antitb_1724 | SEQ ID NO 4 | ELNNALQNLART | Free | Free | None | Linear | 12 | L | NA | Protein Derived | From the proetins containing mycobacterial CD8 T cell epitopes | Mycobacterium tuberculosis | Mycobacterium tuberculosis | NA | In vitro | PBMcs | NA | NA | β2-microglobulin gene knowckout mice, TAP-1 null mutant mice and HSP-65 immunized mice | NA | IFN-γ release increases | By CD8 T cell response | NA | None | None | 2002 | US 2002/013197 |
| antitb_1725 | SEQ ID NO 7 | SGSEAYQGVQQKWDA | Free | Free | None | Linear | 15 | L | NA | Protein Derived | From the proetins containing mycobacterial CD8 T cell epitopes | Mycobacterium tuberculosis | Mycobacterium tuberculosis | NA | In vitro | PBMcs | NA | NA | β2-microglobulin gene knowckout mice, TAP-1 null mutant mice and HSP-65 immunized mice | NA | IFN-γ release increases | By CD8 T cell response | NA | None | None | 2002 | US 2002/013197 |
| antitb_1726 | SEQ ID NO 8 | TATELNNAL | Free | Free | None | Linear | 9 | L | NA | Protein Derived | From the proetins containing mycobacterial CD8 T cell epitopes | Mycobacterium tuberculosis | Mycobacterium tuberculosis | NA | In vitro | PBMcs | NA | NA | β2-microglobulin gene knowckout mice, TAP-1 null mutant mice and HSP-65 immunized mice | NA | IFN-γ release increases | By CD8 T cell response | NA | None | None | 2002 | US 2002/013197 |
| antitb_1727 | SEQ ID NO 9 | RTISEAGQAM | Free | Free | None | Linear | 10 | L | NA | Protein Derived | From the proetins containing mycobacterial CD8 T cell epitopes | Mycobacterium tuberculosis | Mycobacterium tuberculosis | NA | In vitro | PBMcs | NA | NA | β2-microglobulin gene knowckout mice, TAP-1 null mutant mice and HSP-65 immunized mice | NA | IFN-γ release increases | By CD8 T cell response | NA | None | None | 2002 | US 2002/013197 |
| antitb_1728 | SEQ ID NO 10 | AYQGVQQKW | Free | Free | None | Linear | 9 | L | NA | Protein Derived | From the proetins containing mycobacterial CD8 T cell epitopes | Mycobacterium tuberculosis | Mycobacterium tuberculosis | NA | In vitro | PBMcs | NA | NA | β2-microglobulin gene knowckout mice, TAP-1 null mutant mice and HSP-65 immunized mice | NA | IFN-γ release increases | By CD8 T cell response | NA | None | None | 2002 | US 2002/013197 |
| antitb_1729 | SEQ ID NO 11 | SEAYQGVQQ | Free | Free | None | Linear | 9 | L | NA | Protein Derived | From the proetins containing mycobacterial CD8 T cell epitopes | Mycobacterium tuberculosis | Mycobacterium tuberculosis | NA | In vitro | PBMcs | NA | NA | β2-microglobulin gene knowckout mice, TAP-1 null mutant mice and HSP-65 immunized mice | NA | IFN-γ release increases | By CD8 T cell response | NA | None | None | 2002 | US 2002/013197 |
| antitb_1730 | SEQ ID NO 12 | SEAYQGVQQK | Free | Free | None | Linear | 10 | L | NA | Protein Derived | From the proetins containing mycobacterial CD8 T cell epitopes | Mycobacterium tuberculosis | Mycobacterium tuberculosis | NA | In vitro | PBMcs | NA | NA | β2-microglobulin gene knowckout mice, TAP-1 null mutant mice and HSP-65 immunized mice | NA | IFN-γ release increases | By CD8 T cell response | NA | None | None | 2002 | US 2002/013197 |
| antitb_1731 | Seq ID No 10 | KMHATNHGGGS | Free | Free | None | Linear | 11 | L | NA | Synthetic | From random peptide libraries diplayed on bacteriophage M13 | Mycobacterium tuberculosis | Mycobacterium tuberculosis | 100 μM completely inhibits the cahpaeron activity of Hsp 16.3 | In vitro | Mouse bone marrow derive dmacrophages and THP-1 | NA | NA | None | NA | NA | Inhibit chaperon activity of heat shock protein 16.3 (Hsp 16.3) | Heat shock protein (Hsp 16.3) | None | None | 2007 | US 2007/003721 |
| antitb_1732 | Seq ID No 22 | YPHHFKHRHIPIGGGS | Free | Free | None | Linear | 16 | L | NA | Synthetic | From random peptide libraries diplayed on bacteriophage M14 | Mycobacterium tuberculosis | Mycobacterium tuberculosis | 100 μM completely inhibits the cahpaeron activity of Hsp 16.3 | In vitro | Mouse bone marrow derive dmacrophages and THP-1 | NA | NA | None | NA | NA | Inhibit chaperon activity of heat shock protein 16.3 (Hsp 16.3) | Heat shock protein (Hsp 16.3) | None | None | 2007 | US 2007/003721 |
| antitb_1733 | Seq ID No 1 | GVENVSW | Free | Free | None | Linear | 7 | L | NA | Synthetic | From random peptide libraries diplayed on bacteriophage M15 | Mycobacterium tuberculosis | Mycobacterium tuberculosis | 100 μM completely inhibits the cahpaeron activity of Hsp 16.3 | In vitro | Mouse bone marrow derive dmacrophages and THP-1 | NA | NA | None | NA | NA | Inhibit chaperon activity of heat shock protein 16.3 (Hsp 16.3) | Heat shock protein (Hsp 16.3) | None | None | 2007 | US 2007/003721 |
| antitb_1734 | Seq ID No 2 | KMHATNH | Free | Free | None | Linear | 7 | L | NA | Synthetic | From random peptide libraries diplayed on bacteriophage M16 | Mycobacterium tuberculosis | Mycobacterium tuberculosis | 100 μM completely inhibits the cahpaeron activity of Hsp 16.3 | In vitro | Mouse bone marrow derive dmacrophages and THP-1 | NA | NA | None | NA | NA | Inhibit chaperon activity of heat shock protein 16.3 (Hsp 16.3) | Heat shock protein (Hsp 16.3) | None | None | 2007 | US 2007/003721 |
| antitb_1735 | Seq ID No 9 | KMHATNHGGGS | Free | Free | None | Linear | 11 | L | NA | Synthetic | From random peptide libraries diplayed on bacteriophage M17 | Mycobacterium tuberculosis | Mycobacterium tuberculosis | 100 μM completely inhibits the cahpaeron activity of Hsp 16.3 | In vitro | Mouse bone marrow derive dmacrophages and THP-1 | NA | NA | None | NA | NA | Inhibit chaperon activity of heat shock protein 16.3 (Hsp 16.3) | Heat shock protein (Hsp 16.3) | None | None | 2007 | US 2007/003721 |
| antitb_1736 | Seq ID No 21 | YPHHFKHRHIPI | Free | Free | None | Linear | 12 | L | NA | Synthetic | From random peptide libraries diplayed on bacteriophage M18 | Mycobacterium tuberculosis | Mycobacterium tuberculosis | 100 μM completely inhibits the cahpaeron activity of Hsp 16.3 | In vitro | Mouse bone marrow derive dmacrophages and THP-1 | NA | NA | None | NA | NA | Inhibit chaperon activity of heat shock protein 16.3 (Hsp 16.3) | Heat shock protein (Hsp 16.3) | None | None | 2007 | US 2007/003721 |
| antitb_1776 | Sesquin | KTCENLADTY | Free | Free | None | Linear | 10 | L | Cationic | Natural | Isolated from ground beans (Vigna sesquipedalis cv. ‘Ground Bean’) | Mycobacterium phlei | Mycobacterium phlei | IC50 = 87 ± 5 µM | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Antibacterial, Antifungal | 2005 | 15949629 |
| antitb_1806 | NK-2 | KILRGVCKKIMRTFLRRISKDILTGKK | Free | Amidation | None | Linear | 27 | L | Cationic | Protein Derived | Core region of the lymphocytic effector protein NK-lysin | Mycobacterium smegmatis | Mycobacterium smegmatis mc2155 | After 24 h more than 70% killing of M. smegmatis was found at 30 μM | In vitro | mouse macrophage RAW 264.7 | 10 μM NK-2 diminished the intracellular bacterial loadwhen compared to the untreated macrophages | Non-toxic | NA | NA | NA | NA | NA | NA | NA | 2011 | 21396418 |
| antitb_1807 | NK-3 | KILRGVCKKIMRTFLRRISKDILTGKK | Free | Amidation | None | Linear | 27 | L | Cationic | Protein Derived | Core region of the lymphocytic effector protein NK-lysin | Mycobacterium bovis | Mycobacterium bovis BCG Pasteur (ATCC35734) | After 24 h, more than 78% killing was observed at 30 μM | In vitro | mouse macrophage RAW 264.8 | 11 μM NK-2 diminished the intracellular bacterial loadwhen compared to the untreated macrophages | Non-toxic | NA | NA | NA | NA | NA | NA | NA | 2011 | 21396418 |
| antitb_1808 | Ci-MAM-A24 | WRSLGRTLLRLSHALKPLARRSGW | Free | Amidation | None | Linear | 24 | L | Cationic | Protein Derived | Derived from immune cells of Ciona intestinalis, | Mycobacterium smegmatis | Mycobacterium smegmatis mc2155 | 45% bacterial population was killed at 10 μM peptide incubated for 1 hr | In vitro | mouse macrophage RAW 264.9 | NA | Slight toxic (two-fold decrease in cell viability was observed at 50 μM | NA | NA | NA | NA | NA | NA | NA | 2011 | 21396418 |
| antitb_1809 | Ci-MAM-A25 | WRSLGRTLLRLSHALKPLARRSGW | Free | Amidation | None | Linear | 24 | L | Cationic | Protein Derived | Derived from immune cells of Ciona intestinalis, | Mycobacterium bovis | Mycobacterium bovis BCG Pasteur (ATCC35734) | After 24 h, more than 78% killing was observed at 30 μM | In vitro | mouse macrophage RAW 264.10 | NA | Slight toxic (two-fold decrease in cell viability was observed at 50 μM | NA | NA | NA | NA | NA | NA | NA | 2011 | 21396418 |
| antitb_1811 | LL- 37 | LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES | Free | Free | None | Linear | 37 | L | Cationic | Natural | Human cells | Mycobacterium tuberculosis | Mycobacterium tuberculosis strain H37Rv | MIC = 5 μM | Both | NA | NA | NA | Male BALB/c mice | a significant reduction in bacilli loads | NA | Disruption of cell wall and membrane | cell wall and membrane | NA | Antibacterial (P.aeruginosa) | 2012 | 23141114 |
| antitb_1812 | mouse CRAMP | GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPEQ | Free | Free | None | Linear | 34 | L | Cationic | Natural | Mouse cells | Mycobacterium tuberculosis | Mycobacterium tuberculosis strain H37Rv | MIC = 4 μM | Both | NA | NA | NA | Male BALB/c mice | a significant reduction in bacilli loads | NA | Disruption of cell wall and membrane | cell wall and membrane | NA | Antibacterial (P.aeruginosa) | 2012 | 23141114 |
| antitb_1813 | E2 (also known as Bac8c) | RIWVIWRR | Free | Amidation | None | Linear | 8 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis strain H37Rv | MIC = 2.6 ± 0.34 g/mL | Both | NA | NA | NA | Male BALB/c mice | a significant reduction in bacilli loads | NA | Disruption of cell wall and membrane | cell wall and membrane | NA | Antibacterial (P.aeruginosa) | 2012 | 23141114 |
| antitb_1814 | E6 (also called Sub3) | RRWRIVVIRVRR | Free | Amidation | None | Linear | 12 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis strain H37Rv | MIC = 3.2 ± 0.10 g/mL | Both | NA | NA | NA | Male BALB/c mice | a significant reduction in bacilli loads | NA | Disruption of cell wall and membrane | cell wall and membrane | NA | Antibacterial (P.aeruginosa) | 2012 | 23141114 |
| antitb_1815 | CP26 | KWKSFIKKLTSAAKKVVTTAKPLISS | Free | Free | None | Linear | 26 | L | Cationic | Protein Derived | derived from a hybrid peptide comprising the amphipathic α -helical Nterminal region of cecropin A and the hydrophobic N-terminal α-helix of the bee venom peptide melittin | Mycobacterium tuberculosis | Mycobacterium tuberculosis strain H37Rv | MIC = 2.1 ± 0.33 g/mL | Both | NA | NA | NA | Male BALB/c mice | a significant reduction in bacilli loads | NA | Disruption of cell wall and membrane | cell wall and membrane | NA | Antibacterial (P.aeruginosa) | 2012 | 23141114 |
| antitb_1816 | ubiquitin-derived peptide Ub2 | STLHLVLRLRGG | Free | Free | None | Linear | 12 | L | Cationic | Protein Derived | Ubiquitin derived | Mycobacterium smegmatis | Mycobacterium smegmatis mc2155 | MIC = 50 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1817 | Ub2scr | RLGRLVSLHTLG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub2 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2156 | MIC > 400 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1818 | Ub2S1A | ATLHLVLRLRGG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub3 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2157 | MIC = 25 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1819 | Ub2T2A | SALHLVLRLRGG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub4 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2158 | MIC = 50 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |