| Primary information |
|---|
| ID | antitb_1807 |
| Peptide Name | NK-3 |
| Sequence | KILRGVCKKIMRTFLRRISKDILTGKK |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Length | 27 |
| Chirality | L |
| Nature | Cationic |
| Source | Protein Derived |
| Origin | Core region of the lymphocytic effector protein NK-lysin |
| Species | Mycobacterium bovis |
| Strain | Mycobacterium bovis BCG Pasteur (ATCC35734) |
| Inhibition Concentartion | After 24 h, more than 78% killing was observed at 30 μM |
| In vitro/In vivo | In vitro |
| Cell Line | mouse macrophage RAW 264.8 |
| Inhibition Concentartion | 11 μM NK-2 diminished the intracellular bacterial loadwhen compared to the untreated macrophages |
| Cytotoxicity | Non-toxic |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Response | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | NA |
| Other Activities | NA |
| Pubmed ID | 21396418 |
| Year of Publication | 2011 |
| 3-D Structure | NA |