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Browse result page of AntiTbPdb

The total number entries retrieved from this search are 547
IDNameSequenceN-Terminal ModificationC-Terminal ModificationChemical ModificationLinear/CyclicLengthChiralityNatureSourceOriginSpeciesStrainInhibition ConcentrationIn vitro/ In vivoCell LineIntracellular InhibitionCytotoxicityAnimal ModelEffective Dose in model organismImmune ResponceMechanism of ActionTargetCombination TherapyOther ActivitiesYear of PublicationPubmed ID/ Patent No.
antitb_1443A2-Ag85B KLVANNTRL FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Ag85B Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1444A2-Ag85B FIYAGSLSA FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Ag85B Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1445A2-ESAT6 AMASTEGNV FreeFreeNoneLinear9LNAProtein derivedMTB derived protein ESAT6 Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1446A2-ESAT LLDEGKQSL FreeFreeNoneLinear9LNAProtein derivedMTB derived protein ESAT6 Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1447A2-Rv2958 ALADLPVTV FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Rv2958 Mycobacterium tuberculosisMycobacterium tuberculosis Rv2958 NANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1448A2-Rv2957 SIIIPTLNV FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Rv2958 Mycobacterium tuberculosisMycobacterium tuberculosis Rv2958 NANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1449A2-Rv0447 VLAGSVDEL FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Rv0447 Mycobacterium tuberculosisMycobacterium tuberculosis Rv0447NANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1450A24-TB10.4 IMYNYPAML FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Rv0447 Mycobacterium tuberculosisMycobacterium tuberculosis Rv0447NANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1451A24-Ag85B WYYQSGLSI FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Ag85B Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1452A24-Ag85B FLTSELPQW FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Ag85B Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1453A24-Ag85B IYAGSLSAL FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Ag85B Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1454A24-ESAT6 AYQGVQQKW FreeFreeNoneLinear9LNAProtein derivedMTB derived protein ESAT6 Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1455A24-ESAT6 ELNNALQNL FreeFreeNoneLinear9LNAProtein derivedMTB derived protein ESAT6 Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1456A24-Rv2958 KYIAADRKI FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Rv2958 Mycobacterium tuberculosisMycobacterium tuberculosis Rv2958 NANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1457A24-Rv2957 PYNLRYRVL FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Rv2958 Mycobacterium tuberculosisMycobacterium tuberculosis Rv2958 NANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1458A24-Rv0447 KYIFPGGLL FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Rv0447 Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1459A3001-TB10.4 QIMYNYPAM FreeFreeNoneLinear9LNAProtein derivedMTB derived protein TB10.4 Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1460A3001-TB10.4 LVRAYHAMS FreeFreeNoneLinear9LNAProtein derivedMTB derived protein TB10.4 Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1461A3001-Rv2957 IVLVRRWPK FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Rv2957Mycobacterium tuberculosisMycobacterium tuberculosis Rv2957NANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1462A3002-TB10.4 QIMYNYPAM FreeFreeNoneLinear9LNAProtein derivedMTB derived protein TB10.4 Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1463A3002-TB10.4 IMYNYPAML FreeFreeNoneLinear9LNAProtein derivedMTB derived protein TB10.4 Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1464A3002-TB10.4 AMEDLVRAY FreeFreeNoneLinear9LNAProtein derivedMTB derived protein TB10.4 Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1465A3002-ESAT6 AMASTEGNV FreeFreeNoneLinear9LNAProtein derivedMTB derived protein ESAT6 Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1466A3002-Rv2958 SARLAGIPY FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Rv2958 Mycobacterium tuberculosisMycobacterium tuberculosis Rv2958 NANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1467A3002-Rv0447 RMWELYLAY FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Rv0447 Mycobacterium tuberculosisMycobacterium tuberculosis Rv2958 NANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1468A68-TB10.4 HAMSSTHEA FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Rv0447 Mycobacterium tuberculosisMycobacterium tuberculosis Rv0447NANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1469A68-TB10.4 ANTMAMMAR FreeFreeNoneLinear9LNAProtein derivedMTB derived protein TB10.4 Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1470A68-Ag85B LPQWLSANR FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Ag85B Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1471A68-Ag85B WGAQLNAMK FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Ag85B Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1472A68-Rv2958 AAPEPVARR FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Rv2958Mycobacterium tuberculosisMycobacterium tuberculosis Rv2958 NANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1473A68-Rv2957 LVYGDVIMR FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Rv2957Mycobacterium tuberculosisMycobacterium tuberculosis Rv2957NANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1474A68-Rv0447 AASAAIANR FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Rv0447Mycobacterium tuberculosisMycobacterium tuberculosis Rv0447NANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1475B58-Ag85B QTYKWETFL FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Ag85B Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1476Cw07-Ag85B ANNTRLWVY FreeFreeNoneLinear9LNAProtein derivedMTB derived protein Ag85B Mycobacterium tuberculosisMycobacterium tuberculosis RvNANANANANANA NAIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatmentDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy. CD8+ T-cellNANA210425809751
antitb_1514Hirsutatins Anot availableFreeFreeNoneBranched cyclic0DCationicNaturalDerived from HirsutellaniveaMycobacterium tuberculosisMycobacterium tuberculosis H37RvMIC =50 mg/mlin vitroNANANANA NANANANANANA201525681127
antitb_1515Hirsutatins Bnot availableFreeFreeNoneBranched cyclic0DCationicNaturalDerived from HirsutellaniveaMycobacterium tuberculosisMycobacterium tuberculosis H37RvMIC = 50 mg/mlin vitroNANANANA NANANANANANA201525681127
antitb_1516PR-39RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFPFreeFreeNoneLinear39LCationicNaturalDerived from pig porcineMycobacterium tuberculosisMycobacterium tuberculosis H37RvReduction in growth is inhibited to to 30 % at conc. 6.25 mg/Lin vitroNANANANA NANANANANAAntibacterial against E.coli, S.aureus, bacillus, pseudomonas201525681127
antitb_1517PR-39RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFPFreeFreeNoneLinear39LCationicNaturalDerived from pig porcineMycobacterium tuberculosisMycobacterium tuberculosis H37RvReduction in growth is inhibited to to80% at conc. 50 mg/Lin vitroNANANANA NANANANANAAntibacterial against E.coli, S.aureus, bacillus, pseudomonas201525681127
antitb_1518PR-39RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFPFreeFreeNoneLinear39LCationicNaturalDerived from pig porcineMycobacterium tuberculosisMycobacterium tuberculosis H37RvIC50 = 17± 9 mg/Lin vitroNANANANA NANANANANAAntibacterial against E.coli, S.aureus, bacillus, pseudomonas201525681127
antitb_1519PR-39RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFPFreeFreeNoneLinear39LCationicNaturalDerived from pig porcineMycobacterium tuberculosisMycobacterium tuberculosis E1380/94 (MDR resistant stain)IC50= 93± 12 mg/Lin vitroNANANANA NANANANANAAntibacterial against E.coli, S.aureus, bacillus, pseudomonas201525681127
antitb_1520PR-39RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFPFreeFreeNoneLinear39LCationicNaturalDerived from pig porcineMycobacterium smegmatis Mycobacterium smegmatis susceptible strain50 mg/Lin vitroNANANANA NANANANAAntibacterial against E.coli, S.aureus, bacillus, pseudomonas201525681127
antitb_1521PR-39RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFPFreeFreeNoneLinear39LCationicNaturalDerived from pig porcineMycobacterium tuberculosisMycobacterium tuberculosis H37RvIC50= 50 mg/Lin vitroNANANANA NANANANAAntibacterial against E.coli, S.aureus, bacillus, pseudomonas201525681127
antitb_1522PR-39RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFPFreeFreeNoneLinear39LCationicNaturalDerived from pig porcineMycobacterium tuberculosisMycobacterium tuberculosis E1380/94 (MDR resistant stain)IC50= 50 mg/Lin vitroNANANANA NANANANAAntibacterial against E.coli, S.aureus, bacillus, pseudomonas201525681127
antitb_1523PR-39RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFPFreeFreeNoneLinear39LCationicNaturalDerived from pig porcineMycobacterium avium Mycobacterium avium susceptible strainMIC= 50 mg/Lin vitroNANANANA NANANANAAntibacterial against E.coli, S.aureus, bacillus, pseudomonas201525681127
antitb_1524NK-LysinNEDTVTQAASRVCDKMKILRGVCKKIMRTFLRRISKDFreeFreeNoneLinear36LCationicSyntheticNAMycobacterium tuberculosisMycobacterium tuberculosis H37RvReduction in bacterial growth inhibiton to 60% at conc. Of 9.37 mg/Lin vitroNANANANA NANAInteacting with microbial membraneNANAAntibacterial against E.coli, S.aureus, bacillus, pseudomonas201525681127
antitb_1525N22VCEHIHLIRGLCHHLMHSYIKRFreeFreeNoneLinear21LCationicSyntheticNAMycobacterium tuberculosisMycobacterium tuberculosis H37RvReduction in bacterial growth inhibiton to 59% at conc. Of 50 mg/L in vitroNANALow toxicity to erythrocyteNA NAInteacting with microbial membraneNANAAntibacterial against E.coli, S.aureus, bacillus, pseudomonas201525681127
antitb_1526NKLF2VCDKMKILRGVCKKIMRSFLRRFreeFreeNoneLinear21LCationicSyntheticNAMycobacterium tuberculosisMycobacterium tuberculosis H37RvNAin vitroNANANANA NAInteacting with microbial membraneNANAAntibacterial against E.coli, S.aureus, bacillus, pseudomonas201525681127
antitb_1528LL-37LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTESFreeFreeNoneLinear37LCationicProtein derivedDerived from Human cationic antimicrobial protein 18 (hCAP18)Mycobacterium tuberculosisMycobacterium tuberculosis H37RvMIC = 2.1 μg/mlin vitroHuman macrophage THP1NANo cytotoxicityC57BL/6 Mice NAInduce expression of IL-8 and MCP-1In vitro binding of bacterilamembrane and induce pore formation while in vivo activate TLR and monocyte to kill bacteriaBacterial cell membrane NANA201525613372
antitb_1529LLKKK-18KEFKRIVKRIKKFLRKLVFreeFreeNoneLinear18LCationicProtein derivedDerived from Human cationic antimicrobial protein 18 (hCAP18)Mycobacterium tuberculosisMycobacterium tuberculosis H37RvMIC = 25 μg/mlin vitroHuman macrophage THP1NANo cytotoxicityNA NAInduce expression of IL-8 and MCP-1In vitro binding of bacterilamembrane and induce pore formation while in vivo activate TLR and monocyte to kill bacteriaBacterial cell membrane NANA201525613372
antitb_1530D5KWKSFLKTFKSLKKTKLHTLLKLISSAcetylationAmidationNoneLinear27LCationicProtein derivedDerived from Human cationic antimicrobial protein 18 (hCAP18)Mycobacterium tuberculosisMycobacterium tuberculosis H37RvMIC = 35.2 μg/mlin vitroHuman macrophage THP1NANo cytotoxicityNA NAInduce expression of IL-8and MCP-1In vitro binding of bacterilamembrane and induce pore formation while in vivo activate TLR and monocyte to kill bacteriaBacterial cell membrane NANA201525613372