Peptide Viewer page of TumorHoPe - A Database of Tumor Homing Peptides
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Metadata
SequenceSVSVGMKPSPRP
MotifPSP
Target TumorLung and Prostate cancer
Year2007
ReceptorsNA
Detailed Data
ID1373
ReferenceLee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65.
Name SourcePC5-52
Phage DisplayM13 phage/random peptide library
In VitroCL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels
In VivoSCID mice human cancers including human lung (H460), colon (HCT116), breast (BT483), prostate (PC3), liver (Mahlavu), and pancreatic (PaCa) cancer xenografts
HomingHoming
ConjugateDoxorubicin
PatentUS/ 20100119444A1,US 2010/0260673A1