SAPdb: Entry Card with Detailed Information of Peptide

Welcome to Entry Card of Peptide


Details of SAPdb ID 1573
Primary information
SAPdb_ID1573
PMID21995651
Year2011
NameFmocFG
SequenceFG
N-Terminal ModificationFmoc [or N-(fluorenyl-9-methoxycarbonyl)]
C-Terminal ModificationFree
Non-terminal ModicationNone
Length2
Peptide/Conjugate/MixturePeptide
Conjugate PartnerNone
TechniqueTransmission Electron Microscopy (TEM)
SolventWater + Sodium hydroxide + HCl
MethodFmocdipeptide was suspended in water. Sodium hydroxide (0.5 M) was gradually added to the aqueous suspensions of Fmoc dipeptide until pH 10.5 was reached. The samples were vortexed and sonicated for 1 min to fully dissolve the short peptide amphiphiles. 0.085 M HCl added dropwise to attain desired pH, followed by vortexing and sonication. Sample heated to 75-80 °C fto dissolve the peptide.. The sample was subsequently cooled and maintained at 4 °C for∼12 h (overnight) to promote or maintain gelation.
Concentration1- 20 mmlol/L
pH10.5
Temperature
Intial boiling to 75 -80 °C heating for 2 minutes and followed by cooling at 4 °C
Incubation Period12 hours
Self-Assembly FormationYes
Type of Self-AssemblyTwisted Ribbon
Size of Self-Assembled structureWidth : 34.8 +/- 4.1 nm
Linear/CyclicLinear
Stability of NanostructureNA
CommentNA
Secondary information
Physico-Chemical properties
Physico-Chemical properties
STRUCTURE
Predicted Structure
SMILESN.A.