SAPdb: Entry Card with Detailed Information of Peptide

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Details of SAPdb ID 1489
Primary information
SAPdb_ID1489
PMID22788380
Year2012
NameL-Carnosine (Beta-alanine-L-histidine)
SequenceBeta-AH
N-Terminal ModificationPalmitic acid
C-Terminal ModificationFree
Non-terminal ModicationBeta-A: Beta-alanine
Length2
Peptide/Conjugate/MixtureMixture
Conjugate PartnerDPPC
TechniqueCryo - Transmission Electron Microscopy (TEM)
SolventWater
MethodA weighted amount of DPPC+C16-βAH was dissolved in ethanol in a 100 mL round-bottom flask. The ethanol was removed to form a thin DPPC film on the walls of the flask under reduced pressure using a rotary evaporator. Any residual solvent was removed under a stream of N2. A weighed amount of water was then added. The flask was then returned to the rotoevaporator, immersed in a water bath, and vigorously rotated for ∼5 min, to reconstitute the lipid film at 50 °C. The solution was thenput in a flask and vortexed at 50 °C for an additional 5 min
Concentration1 %wt
pH6.5 - 1.5
Temperature
50 °C
Incubation Period5 - 10 minutes
Self-Assembly FormationYes
Type of Self-AssemblyVesicles
Size of Self-Assembled structure∼0.07 to 7.2 μm
Linear/CyclicLinear
Stability of NanostructureNA
CommentNA
Secondary information
Physico-Chemical properties
Physico-Chemical properties
STRUCTURE
Predicted Structure
SMILESN.A.