SAPdb: Entry Card with Detailed Information of Peptide

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Details of SAPdb ID 1444
Primary information
SAPdb_ID1444
PMID24085660
Year2013
NameFmoc-LG
SequenceLG
N-Terminal ModificationFmoc [or N-(fluorenyl-9-methoxycarbonyl)]
C-Terminal ModificationFree
Non-terminal ModicationNone
Length2
Peptide/Conjugate/MixturePeptide
Conjugate PartnerNone
TechniqueTransmission Electron Microscopy (TEM) and WAXS(Wide Angle X - Ray scattering)
SolventWater + 0.1M Hcl + 0.5 M NaOH
MethodFmoc-dipeptide was suspended in water. Sodium hydroxide (0.5 M) was gradually added to the aqueous suspensions of Fmoc-dipeptide until pH 10.5 was reached. The samples were vortexed and sonicated for one minute to fully dissolve the peptide amphiphiles. To obtain required pH, a required volume of dilute hydrochloric acid (0.085 M) was then added dropwise to the solution. Solution sonicated and vortexed. Next, the samples were heated to 75–80 ◦C until fully dissolved and homogenised. The samples were subsequently cooled and maintained at 4 ◦C for ∼ 12 hours (overnight) to promote gelation.
Concentration10mmol/L
pH10.5
Temperature
4 °C
Incubation Period~ 12 hours
Self-Assembly FormationNo
Type of Self-AssemblyNo hydogel formation
Size of Self-Assembled structureNA
Linear/CyclicLinear
Stability of NanostructureNA
CommentNA
Secondary information
Physico-Chemical properties
Physico-Chemical properties
STRUCTURE
Predicted Structure
SMILESN.A.