Details of SAPdb ID 1442 |
Primary information | ||
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SAPdb_ID | 1442 | |
PMID | 24085660 | |
Year | 2013 | |
Name | Fmoc-LL | |
Sequence | LL | |
N-Terminal Modification | Fmoc [or N-(fluorenyl-9-methoxycarbonyl)] | |
C-Terminal Modification | Free | |
Non-terminal Modication | None | |
Length | 2 | |
Peptide/Conjugate/Mixture | Peptide | |
Conjugate Partner | None | |
Technique | Transmission Electron Microscopy (TEM) and WAXS(Wide Angle X - Ray scattering) | |
Solvent | Water + 0.1M Hcl + 0.5 M NaOH | |
Method | Fmoc-dipeptide was suspended in water. Sodium hydroxide (0.5 M) was gradually added to the aqueous suspensions of Fmoc-dipeptide until pH 10.5 was reached. The samples were vortexed and sonicated for one minute to fully dissolve the peptide amphiphiles. To obtain required pH, a required volume of dilute hydrochloric acid (0.085 M) was then added dropwise to the solution. Solution sonicated and vortexed. Next, the samples were heated to 75‚Äì80 ‚ó¶C until fully dissolved and homogenised. The samples were subsequently cooled and maintained at 4 ‚ó¶C for ‚à º 12 hours (overnight) to promote gelation. | |
Concentration | 10mmol/L | |
pH | 8 - 10.5 | |
Temperature | 4 °C | |
Incubation Period | ~ 12 hours | |
Self-Assembly Formation | No | |
Type of Self-Assembly | No hydogel formation | |
Size of Self-Assembled structure | NA | |
Linear/Cyclic | Linear | |
Stability of Nanostructure | NA | |
Comment | NA | |
Secondary information | ||
Physico-Chemical properties |
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STRUCTURE |
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SMILES | N.A. |