SAPdb: Entry Card with Detailed Information of Peptide

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Details of SAPdb ID 1227
Primary information
SAPdb_ID1227
PMID25384556
Year2015
NameCompound A
SequenceKK
N-Terminal ModificationAcetylation
C-Terminal ModificationAmidation
Non-terminal ModicationNone
Length2
Peptide/Conjugate/MixtureConjugate
Conjugate PartnerCamptothecin (CPT) -conjugated
TechniqueTransmission Electron Microscopy (TEM)
SolventPhosphate buffer saline
MethodSamples were prepared by dissolving CPT–dipeptides in PBS (10 mm), then diluting to 1 mm after 24 h.
ConcentrationPreincubation at 10mM for 24 h, 1mM for rest 48 hours
pH7.4
Temperature
37 °C
Incubation Period72 hours
Self-Assembly FormationYes
Type of Self-AssemblyNanotubes
Size of Self-Assembled structureDiameter 80–120 nm; Length : several micrometer
Linear/CyclicLinear
Stability of NanostructureStable at 37°C
CommentNA
Secondary information
Physico-Chemical properties
Physico-Chemical properties
STRUCTURE
Predicted Structure
SMILESCC(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N