SAPdb: Entry Card with Detailed Information of Peptide

Welcome to Entry Card of Peptide


Details of SAPdb ID 1121
Primary information
SAPdb_ID1121
PMID21472901
Year2011
Name1 or Boc-{(N-Cbz)-Lys}-Phe-Ala
SequenceKFA
N-Terminal ModificationN-Cbz lysine (Cbz = benzyloxy-carbonyl) and Boc (N-t-Butoxycarbonyl)
C-Terminal ModificationFree
Non-terminal ModicationNone
Length3
Peptide/Conjugate/MixturePeptide derivative
Conjugate PartnerCoupling with 5,5’-dibromomethyl-2,2’-bipyridin
TechniqueTransmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) NMR and Mass spectrometery
SolventTHF (Tetrahydrofuran):Water (1:1)
MethodConjugate 1 was dissolved in THF at a concentration of 4.0mg/mL. Addition of the same amount of water into the prior solution in THF resulted in a transparent solution and the formation of vesicles. Upon ultrasound treatment for about 10 mins, the vesicles transferred into networks of nanofibers
Concentration2mg/ml
pHNA
Temperature
Room temperature
Incubation Period20-30minutes
Self-Assembly FormationYes
Type of Self-AssemblyNanofibril structure
Size of Self-Assembled structurewidth: 50-100nm
Linear/CyclicLinear
Stability of NanostructureStable
CommentNA
Secondary information
Physico-Chemical properties
Physico-Chemical properties
STRUCTURE
Predicted Structure
SMILESN.A.