Details of SAPdb ID 1121 |
Primary information | ||
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SAPdb_ID | 1121 | |
PMID | 21472901 | |
Year | 2011 | |
Name | 1 or Boc-{(N-Cbz)-Lys}-Phe-Ala | |
Sequence | KFA | |
N-Terminal Modification | N-Cbz lysine (Cbz = benzyloxy-carbonyl) and Boc (N-t-Butoxycarbonyl) | |
C-Terminal Modification | Free | |
Non-terminal Modication | None | |
Length | 3 | |
Peptide/Conjugate/Mixture | Peptide derivative | |
Conjugate Partner | Coupling with 5,5’-dibromomethyl-2,2’-bipyridin | |
Technique | Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) NMR and Mass spectrometery | |
Solvent | THF (Tetrahydrofuran):Water (1:1) | |
Method | Conjugate 1 was dissolved in THF at a concentration of 4.0mg/mL. Addition of the same amount of water into the prior solution in THF resulted in a transparent solution and the formation of vesicles. Upon ultrasound treatment for about 10 mins, the vesicles transferred into networks of nanofibers | |
Concentration | 2mg/ml | |
pH | NA | |
Temperature | Room temperature | |
Incubation Period | 20-30minutes | |
Self-Assembly Formation | Yes | |
Type of Self-Assembly | Nanofibril structure | |
Size of Self-Assembled structure | width: 50-100nm | |
Linear/Cyclic | Linear | |
Stability of Nanostructure | Stable | |
Comment | NA | |
Secondary information | ||
Physico-Chemical properties |
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STRUCTURE |
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SMILES | N.A. |