SAPdb: Entry Card with Detailed Information of Peptide

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Details of SAPdb ID 1066
Primary information
SAPdb_ID1066
PMID23422591
Year2013
NameD-leu-Phe-Phe
SequencelFF
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-terminal ModicationNone
Length3
Peptide/Conjugate/MixturePeptide
Conjugate PartnerNone
TechniqueCryo - Transmission Electron Microscopy (TEM), AFM (Atomic Force Microscopy), CD (Circular Dichroism spectroscopy), FTIR (Fourier Transform Infrared)
SolventSodium phosphate(0.1M, pH-11.8 and pH5.7)
MethodPeptide (4.0 mg) was added to a solution of sodium phosphate 0.1 M at pH 11.8 (buffer A, 0.3 ml), and dissolution was achieved with sonication (5 min). Gelation was triggered by subsequent addition of an equal volume of 0.1 M sodium phosphate at pH 5.7 (buffer B, 0.3 ml), resulting in a final pH of 7.4.
Concentration4mg/ml
pHFinal - 7.4
Temperature
37 °C
Incubation PeriodNA
Self-Assembly FormationYes
Type of Self-AssemblyHydrogel
Size of Self-Assembled structureNA
Linear/CyclicLinear
Stability of Nanostructure2 - 3 hours
CommentNA
Secondary information
Physico-Chemical properties
Physico-Chemical properties
STRUCTURE
Predicted Structure
SMILESN[C@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)CO