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Details of SAPdb entry with Sequence FV
Primary information
SAPdb ID 1240,
PMID20695592
Peptide NameDipeptide 6
Peptide sequenceFV
N-Terminal ModificationNapthalene
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length2
Peptide/ConjuagateConjugate
Conjugate partnerNapthalene
TechniqueTransmission Electron Microscopy (TEM)
SolventDeionized water + 0.1 M Sodium hydroxide + glucono-Å’Â¥-lactone (GdL)
MethodStock solutions of dipeptide-conjugates at a concentration of (0.5 wt%) were prepared and equimolar NaOH (0.1M ) added to it. These were then diluted with pH 10 water to a number of concentrations. To adjust the pH, for each dipeptide-conjugate solution and required quantity of GdL is added to solution to ensure final pH between 3.2 -3.6. Samples were left to stand at least 24 h.
Conc0.5 wt%
Temperature3.4 +/- 0.2.
TemperatureRoom temperature
Incubation Time24 hours
Year2010
Self assemblyYes
Type of Self assemblyTransparent Gel
Tertiary Structure
(Technique)
Not Predicted),
Linear
NA
NA
Hydrogel
NA
FV
N.A.
Primary information
SAPdb ID 1246,
PMID20695592
Peptide NameDipeptide 12
Peptide sequenceFV
N-Terminal ModificationBromo-Napthalene or napthalene derivative
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length2
Peptide/ConjuagateConjugate
Conjugate partnerNitrile-Napthalene
TechniqueTransmission Electron Microscopy (TEM)
SolventDeionized water + 0.1 M Sodium hydroxide + glucono-Å’Â¥-lactone (GdL)
MethodStock solutions of dipeptide-conjugates at a concentration of (0.5 wt%) were prepared and equimolar NaOH (0.1M ) added to it. These were then diluted with pH 10 water to a number of concentrations. To adjust the pH, for each dipeptide-conjugate solution and required quantity of GdL is added to solution to ensure final pH between 3.2 -3.6. Samples were left to stand at least 24 h.
Conc0.5 wt%
Temperature3.4 +/- 0.2.
TemperatureRoom temperature
Incubation Time24 hours
Year2010
Self assemblyYes
Type of Self assemblyTransparent Gel
Tertiary Structure
(Technique)
Not Predicted),
Linear
NA
NA
Hydrogel
NA
FV
N.A.
Primary information
SAPdb ID 1252,
PMID22468743
Peptide NameDiPhenylalanine
Peptide sequenceFV
N-Terminal ModificationCyano-Napthalene or napthalene derivative
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length2
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueInsilico tools i.e, Coarse - grained molecular dynamics (MD) simulations and GROMACS software
SolventWater
Method40 MD simulations performed on a system consisting of 600 FF peptides at peptide concentrations: 50mg/mL
Conc50 mg/ml
Temperature37 °C
Incubation Time60 - 1200 nanoseconds
Year2012
Self assemblyYes
Type of Self assemblyToroid, ellipsoid, pot shaped and potshaped, and discoid shaped Vesicle like structures
Tertiary Structure
(Technique)
Not Predicted),
Linear
NA
NA
Nanovesicle
NA
FV
N.A.
Primary information
SAPdb ID 1517,
PMID20695592
Peptide NameDipeptide 5
Peptide sequenceFV
N-Terminal ModificationNapthalene
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length2
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueTransmission Electron Microscopy (TEM)
SolventWater + NaOH + 8.75 mg/ml GdL(glucono-delta-lactone)
MethodDipeptide solution mixed with equimolar solution of 0.1M NaOH followd by gentle stirring for 30 minutes to obtain clear solution. Then to lower the pH GdL is added and kept it undisturbed for 24 hours to get gel.
Conc0.5%wt
Temperature3.4 +/- 0.2.
TemperatureRoom temperature
Incubation Time> 24 hours
Year2010
Self assemblyYes
Type of Self assemblyTurbid gel
Tertiary Structure
(Technique)
Not Predicted),
Linear
NA
NA
Hydrogel
NA
FV
N.A.
Primary information
SAPdb ID 1523,
PMID20695592
Peptide NameDipeptide 11
Peptide sequenceFV
N-Terminal ModificationBromo-Napthalene or napthalene derivative
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length2
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueTransmission Electron Microscopy (TEM)
SolventWater + NaOH + 8.75 mg/ml GdL(glucono-delta-lactone)
MethodDipeptide solution mixed with equimolar solution of 0.1M NaOH followd by gentle stirring for 30 minutes to obtain clear solution. Then to lower the pH GdL is added and kept it undisturbed for 24 hours to get gel.
Conc0.5%wt
Temperature3.4 +/- 0.2.
TemperatureRoom temperature
Incubation Time> 24 hours
Year2010
Self assemblyYes
Type of Self assemblyTurbid gel
Tertiary Structure
(Technique)
Not Predicted),
Linear
NA
NA
Hydrogel
NA
FV
N.A.
Primary information
SAPdb ID 1529,
PMID20695592
Peptide NameDipeptide 17
Peptide sequenceFV
N-Terminal ModificationCyano-Napthalene or napthalene derivative
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length2
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueTransmission Electron Microscopy (TEM)
SolventWater + NaOH + 8.75 mg/ml GdL(glucono-delta-lactone)
MethodDipeptide solution mixed with equimolar solution of 0.1M NaOH followd by gentle stirring for 30 minutes to obtain clear solution. Then to lower the pH GdL is added and kept it undisturbed for 24 hours to get gel.
Conc0.5%wt
Temperature3.4 +/- 0.2.
TemperatureRoom temperature
Incubation Time> 24 hours
Year2010
Self assemblyYes
Type of Self assemblyTurbid gel
Tertiary Structure
(Technique)
Not Predicted),
Linear
NA
NA
Hydrogel
NA
FV
N.A.
Primary information
SAPdb ID 1921,
PMID28485150
Peptide NameBocNH-Phe- FFSAA-Val-OMe (9c)
Peptide sequenceFV
N-Terminal ModificationBoc (or t-butoxycarbonyl)
C-Terminal ModificationMethoxy
Non-Terminal Modificationfluorinated furanoid sugar amino acid (FFSAA)
Length2
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueScanning Electron Microscopy (SEM)
SolventHATU
Conc1 mmol
Temperature0 °C
Incubation Time5h
Year2017
Self assemblyNo
Type of Self assemblyNA
Tertiary Structure
(Technique)
Not Predicted),
NA
NA
NA
NA
NA
FV
N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(C(C)C)C(=O)O
Primary information
SAPdb ID 1924,
PMID28485150
Peptide NameBocNH-Phe- SAA-Val-OMe (15c)
Peptide sequenceFV
N-Terminal ModificationBoc (or t-butoxycarbonyl)
C-Terminal ModificationMethoxy
Non-Terminal ModificationSAA
Length2
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueScanning Electron Microscopy (SEM)
SolventCMPI
Conc1 mmol
Temperature0 °C
Incubation Time5h
Year2017
Self assemblyNo
Type of Self assemblyNA
Tertiary Structure
(Technique)
Not Predicted),
NA
NA
NA
NA
NA
FV
N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(C(C)C)C(=O)O