Details of SAPdb entry with Sequence FFK |
Primary information | |
---|---|
SAPdb ID | 1070, |
PMID | 23871602 |
Peptide Name | FFK |
Peptide sequence | FFK |
N-Terminal Modification | Acetylation |
C-Terminal Modification | Amidation |
Non-Terminal Modification | None |
Length | 3 |
Peptide/Conjuagate | Peptide |
Conjugate partner | None |
Technique | AFM (Atomic Force Microscopy), Transmission Electron Microscopy (TEM), DLS (Dynamic Light Scattering) and CD (Circular Dichroism spectroscopy) |
Solvent | Water and HFIP (9.5:0.5, v/v) |
Method | For preparation of FFK solution, the mixture of water and HFIP (9.5:0.5, v/v) was used to dissolve the peptide at 1.0 mg/mL with sonication for 30 min. final solution pH was around 5–6. The peptide solutions were incubated for at least one week |
Conc | 1mg/ml |
Temperature | 5-6 |
Incubation Time | 2 weeks |
Year | 2013 |
Self assembly | Yes |
Type of Self assembly | Long (amyloid like) tubular structure |
Tertiary Structure (Technique) | Not Predicted), |
Linear | |
NA | |
NA | |
Nanotube | |
6 | |
None | |
CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCC[NH3])C(=O)N | |
Primary information | |
SAPdb ID | 1169, |
PMID | 21121607 |
Peptide Name | Hydrogelator 1 |
Peptide sequence | FFK |
N-Terminal Modification | Napthalene |
C-Terminal Modification | Olsalazine |
Non-Terminal Modification | None |
Length | 3 |
Peptide/Conjuagate | Conjugate |
Conjugate partner | Olsalazine |
Technique | Transmission Electron Microscopy (TEM) |
Solvent | Water |
Method | 6.0 mg of peptide dissolved in 0.50 mL of water to give a clear solution, after which a change in pH to 5.0 resulted in a viscous suspension. Ultrasound sonication of the suspension for 2 min or an increase of its temperature to ‚à º60 ¬∞C followed by cooling to ambient temperature afforded a transparent, yellow gel. |
Conc | 1.2 wt% |
Temperature | 5 |
Temperature | Heating at 60 ℃, cooling at RT |
Year | 2010 |
Self assembly | Yes |
Type of Self assembly | Hydrogel containing Nanofibers |
Tertiary Structure (Technique) | Not Predicted), |
Linear | |
NA | |
Stable | |
Hydrogel | |
11 | |
None | |
N.A. | |
Primary information | |
SAPdb ID | 1170, |
PMID | 21121607 |
Peptide Name | Tripeptide 1 |
Peptide sequence | FFK |
N-Terminal Modification | Acetylation |
C-Terminal Modification | Olsalazine |
Non-Terminal Modification | None |
Length | 3 |
Peptide/Conjuagate | Conjugate |
Conjugate partner | Olsalazine |
Technique | Transmission Electron Microscopy (TEM) |
Solvent | Water |
Method | 6.0 mg of peptide dissolved in 0.50 mL of water to give a clear solution, after which a change in pH to 5.0 resulted in a viscous suspension. Ultrasound sonication of the suspension for 2 min or an increase of its temperature to ‚à º60 ¬∞C followed by cooling to ambient temperature afforded a transparent, yellow gel. |
Conc | 1.2 wt% |
Temperature | 5 |
Temperature | Heating at 60 ℃, cooling at RT |
Year | 2010 |
Self assembly | No |
Type of Self assembly | No hydrogel formation |
Tertiary Structure (Technique) | Not Predicted), |
Linear | |
NA | |
Stable | |
None | |
NA | |
None | |
N.A. | |
Primary information | |
SAPdb ID | 1171, |
PMID | 21121607 |
Peptide Name | Hydrogelator 1 |
Peptide sequence | ffk |
N-Terminal Modification | Napthalene |
C-Terminal Modification | Olsalazine |
Non-Terminal Modification | None |
Length | 3 |
Peptide/Conjuagate | Conjugate |
Conjugate partner | Olsalazine |
Technique | Transmission Electron Microscopy (TEM) |
Solvent | Water |
Method | 6.0 mg of peptide dissolved in 0.50 mL of water to give a clear solution, after which a change in pH to 5.0 resulted in a viscous suspension. Ultrasound sonication of the suspension for 2 min or an increase of its temperature to ‚à º60 ¬∞C followed by cooling to ambient temperature afforded a transparent, yellow gel. |
Conc | 1.2 wt% |
Temperature | 5 |
Temperature | Heating at 80 ℃, cooling at RT |
Year | 2010 |
Self assembly | Yes |
Type of Self assembly | Hydrogel containing Nanofibers |
Tertiary Structure (Technique) | Not Predicted), |
Linear | |
NA | |
High biostabilty even on the treatment of proteinase K for 48 hours | |
Hydrogel | |
13 | |
None | |
N.A. | |
Primary information | |
SAPdb ID | 1175, |
PMID | 23240879 |
Peptide Name | Nap-FFK |
Peptide sequence | FFK |
N-Terminal Modification | Napthalene |
C-Terminal Modification | Free |
Non-Terminal Modification | None |
Length | 3 |
Peptide/Conjuagate | Peptide |
Conjugate partner | None |
Technique | Cryo - Transmission Electron Microscopy (TEM) |
Solvent | PBS (Phosphate Buffer Saline) |
Method | 1.0 mg of each peptide and equal molar of sodium carbonate to the peptide were first suspended in PBS buffer (pH = 7.4); the sodium carbonate was used to neutralize the terminal carboxylic acid of peptides. The suspensions were then heated to 80°C to form clear solutions. The gels would form after cooling back to room temperature within 3 min. |
Conc | < 4% wt |
Temperature | 7.4 |
Temperature | Heating at 80 ℃, cooling at RT |
Incubation Time | 3 minutes |
Year | 2012 |
Self assembly | Yes |
Type of Self assembly | Hydrogel |
Tertiary Structure (Technique) | Not Predicted), |
Linear | |
NA | |
NA | |
Hydrogel | |
NA | |
None | |
N.A. | |
Primary information | |
SAPdb ID | 1950, |
PMID | 28638095 |
Peptide Name | Mito-FF (Phe-Phe-Lys (FFK)) |
Peptide sequence | FFK |
N-Terminal Modification | Free |
C-Terminal Modification | Free |
Non-Terminal Modification | None |
Length | 3 |
Peptide/Conjuagate | Peptide |
Conjugate partner | None |
Technique | FT-IR |
Solvent | phosphate-buffered saline (PBS) |
Year | 2017 |
Self assembly | Yes |
Type of Self assembly | Nanofibres |
Tertiary Structure (Technique) | Not Predicted), |
Linear | |
NA | |
NA | |
Nanofiber | |
9.6 | |
None | |
N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCCCN)C(=O)O | |