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Details of SAPdb entry with Sequence F-Delta-F
Primary information
SAPdb ID 1293,
PMID22915849
Peptide NamePhenylalanine-dehydroPhenylalanine (F-Delta-F)
Peptide sequenceF-Delta-F
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationDelta-F or Δphe=alpha-beta-dehydrophenylalanine
Length2
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueTransmission Electron Microscopy (TEM), DLS (Dynamic light - scattering)
SolventMethanol and water (50:50; v/v).
MethodStock solutions were prepared by dissolving 2 mg of peptide in 50 μL of methanol, solution is sonicated to dissolve. Assembly was initiated by addition of 1 mL of aqueous methanol (50% v/v) to the stock. Samples were incubated for 24 hours.
Conc2mg/ml
TemperatureRoom temperature
Incubation Time24 hours
Year2012
Self assemblyNo
Type of Self assemblyNo Nanoparticle formation
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
NA
None
NA
FF
N.A.
Primary information
SAPdb ID 1493,
PMID22833945
Peptide NamePhe-alpha,beta-dehydroPhenylalanine
Peptide sequenceF-Delta-F
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationDelta-F or Δphe=alpha-beta-dehydrophenylalanine
Length2
Peptide/ConjuagatePeptide derivative
Conjugate partnerNone
TechniqueTransmission Electron Microscopy (TEM) and DLS (Dynamic Light scattering)
Solvent1,1,1,3,3,3-hexa-fluoro-isopropanol/water.
MethodStock solutions of dipeptides were prepared by dissolving 0.1–1 mg of them in 50 μl of HFIP. Solution heated and sonicated to dissolve the dipeptide. Assembly was initiated by addition of double-distilled water (1 ml) to the stock solution. Samples were aged 24–48 h before experiments.
Conc0.1 - 1mg/ml
TemperatureRoom temperature
Incubation Time24 -48 hours for sample aging and 30 - 60 minutes for self assembly
Year2010
Self assemblyYes
Type of Self assemblyNanotube
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
Proteolytically stable
Nanotube
17
FF
N.A.
Primary information
SAPdb ID 1498,
PMID18624454
Peptide NamePhe-Delta-Phe (Phenylanaline -dehydroPhenylalanine)
Peptide sequenceF-Delta-F
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationDelta-F or Δphe=alpha-beta-dehydrophenylalanine
Length2
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueTransmission Electron Microscopy (TEM) and DLS (Dynamic Light scattering)
SolventHFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + 0.8M Sodium acetate
MethodA 50 mg/mL HFIP solution of Phe-Δphe added to 0.8 M sodium acetate buffer to get a final concentration between 0.2-1% w/v at pH 7. The mixture was then boiled in a boiling water bath for 15 min or in a microwave oven for 3 min and cooled back to room temperature to form gel.
Conc0.2-1% w/v
Temperature7
TemperatureRoom temperature
Year2008
Self assemblyYes
Type of Self assemblyHydrogel (consists of fibers)
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
Stable under physiological conditions
Hydrogel
NA
FF
N.A.