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Details of RareLSD ID 1064

RareLSD_Id	1064
ENZYME	Thiol reductase, ginterferon inducible
GENE	IFI30
E.C.NUMBER	1.8.-.-
FAMILY	GILT
CYTOGENETICS	19p13.11
DISEASE	atrophic rhinitis
SNP	rs1000028829,rs1001072455,rs1001423445,rs1001838530,rs1001978587
DEPOSIT	NA
REF	10639150, 10852914, 3136170
TEMP (in Celsius)	37
pI	NA
pH	45
Catalytic Nucleophile	Cys49
Catalytic Acid/Base	Cys46
Substrate	F(ab')2 fragment
Product	NA
Structure(PDB/Phyre2_ID)	c3ghaA
kM	10
DRUG	NA
SEQ LENGTH	250
AA SEQ	MTLSPLLLFLPPLLLLLDVPTAAVQASPLQALDFFGNGPPVNYKTGNLYLRGPLKKSNAPLVNVTLYYEALCGGCRAFLIRELFPTWLLVMEILNVTLVPYGNAQEQNVSGRWEFKCQHGEEECKFNKVEACVLDELDMELAFLTIVCMEEFEDMERSLPLCLQLYAPGLSPDTIMECAMGDRGMQLMHANAQRTDALQPPHEYVPWVTVNGKPLEDQTQLLTLVCQLYQGKKPDVCPSSTSSLRSVCFK
MODIFICATION	N-linked Glycosylation:Asn63,Asn95,Asn108
INHIBITOR	NA
ACTIVE SITE RESIDUE	NA
DISULPHIDE BRIDGES	*72-75
PSEUDOGENES	NA
MISCELLANEOUS	Both precursor form and mature form have thiol reductase activity
PARALOGS	NA
MECHANISM	NA
INHERITANCE PATTERN	Autosomal Dominant
ORGAN AFFECTED	Nose
ENZYME LOCATION	OD
UniProt ID	P13284