| RareLSD_Id | 1064 |
| ENZYME | Thiol reductase, ginterferon inducible |
| GENE | IFI30 |
| E.C.NUMBER | 1.8.-.- |
| FAMILY | GILT |
| CYTOGENETICS | 19p13.11 |
| DISEASE | atrophic rhinitis |
| SNP | rs1000028829,rs1001072455,rs1001423445,rs1001838530,rs1001978587 |
| DEPOSIT | NA |
| REF | 10639150, 10852914, 3136170 |
| TEMP (in Celsius) | 37 |
| pI | NA |
| pH | 45 |
| Catalytic Nucleophile | Cys49 |
Catalytic Acid/Base
| Cys46 |
| Substrate | F(ab')2 fragment |
| Product | NA |
| Structure(PDB/Phyre2_ID) | c3ghaA |
| kM | 10 |
| DRUG | NA |
| SEQ LENGTH | 250 |
| AA SEQ | MTLSPLLLFLPPLLLLLDVPTAAVQASPLQALDFFGNGPPVNYKTGNLYLRGPLKKSNAPLVNVTLYYEALCGGCRAFLIRELFPTWLLVMEILNVTLVPYGNAQEQNVSGRWEFKCQHGEEECKFNKVEACVLDELDMELAFLTIVCMEEFEDMERSLPLCLQLYAPGLSPDTIMECAMGDRGMQLMHANAQRTDALQPPHEYVPWVTVNGKPLEDQTQLLTLVCQLYQGKKPDVCPSSTSSLRSVCFK |
| MODIFICATION | N-linked Glycosylation:Asn63,Asn95,Asn108 |
| INHIBITOR | NA |
| ACTIVE SITE RESIDUE | NA |
| DISULPHIDE BRIDGES | *72-75 |
| PSEUDOGENES | NA |
| MISCELLANEOUS | Both precursor form and mature form have thiol reductase activity |
| PARALOGS | NA |
| MECHANISM | NA |
| INHERITANCE PATTERN | Autosomal Dominant |
| ORGAN AFFECTED | Nose |
| ENZYME LOCATION | OD |
| UniProt ID | P13284 |
