Welcome to Entry Card of Lysosomal Enzymes


Details of RareLED ID Assay_1045
Primary information
GENEPPT2
NUMBER OF ASSAY8
ASSAY IDs504510 493154 651990 743118 743127 504482 493110 743119
Assay Name1. Late stage assay provider results from the probe development effort to identify inhibitors of LYPLA1: absorbance-based cell-based dose response assay to determine cytotoxicity of inhibitor compounds set 2,2. Late stage assay provider results from the probe development effort to identify inhibitors of LYPLA1 and LYPLA2: Gel-based Activity-Based Protein Profiling (ABPP) IC50 for off-target ABHD11,3. Late stage assay provider results from the probe development effort to identify selective inhibitors of LYPLA1 and LYPLA2: Fluorescence-based biochemical dose-response gel-based ABPP,4. Late stage assay provider results from the extended probe development effort to identify inhibitors of LYPLA1 and LYPLA2: Fluorescence-based biochemical dose-response gel-based ABPP in vitro,5. Late stage assay provider results from the extended probe development effort to identify inhibitors of LYPLA1 and LYPLA2: Absorbance-based cell-based dose response assay to determine cytotoxicity of inhibitor compounds,6. Late stage assay provider results from the probe development effort to identify inhibitors of LYPLA1: fluorescence-based cell-based gel-based Activity-Based Protein Profiling (ABPP) IC50 for anti-target ABHD11,7. Late stage assay provider results from the probe development effort to identify dual inhibitors of LYPLA1 and LYPLA2: Gel-based Activity-Based Protein Profiling (ABPP) IC50 for LYPLA1 and LYPLA2,8. Late stage assay provider results from the extended probe development effort to identify inhibitors of LYPLA1 and LYPLA2: Fluorescence-based biochemical dose-response gel-based ABPP in situ
ACTIVITYSubstance BioActivity: 2 Tested Substance BioActivity: 2 Active, 2 Activity <= 1 µM, 2 Tested Substance BioActivity: 2 Active, 2 Activity <= 1 µM, 2 Tested Substance BioActivity: 5 Active, 5 Activity <= 1 µM, 5 Tested Substance BioActivity: 2 Tested Substance BioActivity: 2 Active, 2 Activity <= 1 nM, 2 Activity <= 1 µM, 2 Tested Substance BioActivity: 3 Active, 4 Activity <= 1 µM, 5 Tested Substance BioActivity: 1 Active, 1 Activity <= 1 µM, 1 Tested