Welcome to Entry Card of Lysosomal Enzymes


Details of RareLED ID Assay_1038
Primary information
GENEMPO
NUMBER OF ASSAY20
ASSAY IDs701372 701371 738128 547367 1337095 315978 1172273 701379 701373 1264477 1256935 1256933 1256926 738129 547368 1337096 1331722 143578 143576 1070492
Assay Name1. Inhibition of myeloperoxidase,2. Binding affinity to recombinant human myeloperoxidase,3. Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISA,4. Inhibition of recombinant MPO mediated taurine chlorination by microplate reader method,5. Inhibition of human MPO,6. Inhibition of chlorinating activity of recombinant myeloperoxidase by taurine assay,7. Inhibition of myeloperoxidase (unknown origin) assessed as reduction in enzymatic hypochlorous acid production by spectrophotometry based taurine chlorination assay,8. Inhibition of recombinant human myeloperoxidase assessed as taurine chloramine production after 5 mins by spectrophotometry in presence of H2O2,9. Inhibition of recombinant human myeloperoxidase,10. Inhibition of human recombinant myeloperoxidase by amplex red assay,11. Irreversible inhibition of MPO in LPS-stimulated human whole blood after 4 hrs by Amplex Red/H2O2-based fluorescence plate reader analysis,12. Inhibition of peroxidase activity of MPO isolated from human polynuclear leukocytes using Amplex Red as substrate assessed as formation of resorufin measured every 20 secs by spectrophotometric analysis,13. Inhibition of peroxidase activity of MPO isolated from human polynuclear leukocytes using Amplex Red as substrate assessed as formation of resorufin after 300 secs by spectrophotometric analysis,14. Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay,15. Inhibition of recombinant MPO mediated LDL oxidation using MPO/Cl-/H2O2 system,16. Irreversible inhibition of MPO (unknown origin),17. Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS method,18. Compound was evaluated for the inhibition of serum-opsonized zymosan stimulated myeloperoxidase release from human neutrophil,19. In vivo potency as the maximal lysosomal myeloperoxidase (MPO) release in PMNL assay,20. Inhibition of myeloperoxidase (unknown origin) using HOCl/taurine as substrate assessed as inhibition of taurine chloramine production by spectrophotometry
ACTIVITYSubstance BioActivity: 3 Active, 1 Activity <= 1 µM, 3 Tested Substance BioActivity: 1 Active, 1 Tested Substance BioActivity: 24 Active, 28 Activity <= 1 µM, 31 Tested Substance BioActivity: 24 Active, 22 Activity <= 1 µM, 24 Tested Substance BioActivity: 56 Tested Substance BioActivity: 7 Active, 13 Tested Substance BioActivity: 29 Active, 14 Activity <= 1 µM, 38 Tested Substance BioActivity: 8 Active, 3 Activity <= 1 µM, 8 Tested Substance BioActivity: 4 Active, 2 Activity <= 1 µM, 4 Tested Substance BioActivity: 30 Active, 19 Activity <= 1 µM, 36 Tested Substance BioActivity: 9 Active, 2 Activity <= 1 µM, 9 Tested Substance BioActivity: 6 Tested Substance BioActivity: 1 Active, 1 Tested Substance BioActivity: 25 Active, 29 Activity <= 1 µM, 34 Tested Substance BioActivity: 21 Active, 23 Activity <= 1 µM, 24 Tested Substance BioActivity: 2 Active, 1 Activity <= 1 µM, 2 Tested Substance BioActivity: 21 Active, 15 Activity <= 1 µM, 39 Tested Substance BioActivity: 1 Active