Welcome to Entry Card of Lysosomal Enzymes

Details of RareLED ID Assay_1036

Primary information
GENE	MAN2B1
NUMBER OF ASSAY	222
ASSAY IDs	240863 241268 241392 241366 241029 240927 240839 238243 241119 240937 240862 241411 240928 241236 241237 241202 240929 240897 240843 240840 240688 35368 35262 35369 717598 717597 35370 402244 289171 35255 341039 341038 341037 35817 33274 33273 35818 498017 498016 497877 497876 497875 497874 497872 497873 241075 240953 238644 238641 238589 235911 35254 35225 513874 513873 513872 513871 513870 513869 513868 513867 513866 513865 513864 513863 513855 37265 37140 341036 341035 717726 717599 514937 514936 514935 514934 514933 514932 514931 514930 514929 514928 514927 514926 514925 514924 514923 514922 514906 514905 514904 514903 514902 514901 514900 514899 514898 514897 513854 37420 37409 341048 341041 341040 40300 40299 40162 39990 39986 479009 479008 479007 479006 479005 479004 479003 479002 108106 513875 513861 513858 513856 402245 296106 587710 514907 514895 5146
Assay Name	1. Inhibitory concentration against human alpha-mannosidase,2. Inhibitory concentration against alpha-mannosidase of rat epididymis,3. Inhibitory concentration against alpha-L-fucosidase of bovine epididymis,4. Inhibitory concentration against bovine alpha-L-fucosidase,5. Inhibitory concentration against human alpha-L-fucosidase,6. Inhibitory concentration against human alpha-fucosidase,7. Inhibitory concentration against human alpha-fucosidase,8. Ki value against bovine alpha-L-fucosidase,9. Inhibitory concentration against alpha-mannosidase of jack bean,10. Inhibitory concentration against human alpha-galactosidase,11. Inhibitory concentration against human alpha-glucosidase,12. Inhibitory concentration against alpha-galactosidase of Aspergillus niger,13. Inhibitory concentration against rice alpha-glucosidase,14. Inhibitory concentration against alpha-galactosidase of coffee bean,15. Inhibitory concentration against beta-galactosidase of bovine liver,16. Inhibitory concentration against beta-galactosidase of bovine liver,17. Inhibitory concentration against beta-galactosidase of rat,18. Inhibitory concentration against human beta-galactosidase,19. Inhibitory concentration against rat intestinal maltase,20. Inhibitory concentration against human beta-glucosidase,21. Inhibitory concentration against beta-glucosidase,22. Competitive Inhibitory activity against Golgi Alpha-mannosidase II,23. Inhibition of golgi Alpha-mannosidase II in rat liver,24. Inhibition of lysosomal Alpha-mannosidase II in rat liver,25. Inhibition of human ER alpha mannosidase 1,26. Inhibition of human golgi alpha mannosidase 2,27. Inhibition of soluble Alpha-mannosidase II in rat liver,28. Inhibition of rat epididymis alpha-mannosidase by spectrophotometry,29. Inhibition of jack bean alpha-mannosidase,30. Compound was tested for the inhibitory activity against alpha-mannosidase,31. Inhibition of alpha-mannosidase in human HCEC,32. Inhibition of alpha-mannosidase in human LN18 cells,33. Inhibition of alpha-mannosidase in human LNZ308 cells,34. Tested for competitive inhibition of golgi alpha mannosidase II,35. Concentration that causes 50% inhibition of mammalian alpha-mannosidase (Golgi II) was determined in rat liver,36. Concentration that causes 50% inhibition of mammalian alpha-mannosidase (Golgi I) was determined in rat liver,37. Tested for competitive inhibition of golgi-alpha-mannosidase II,38. Inhibition of Bacteroides thetaiotaomicron beta-mannosidase 2A N461A mutant expressed in Escherichia coli assessed as inhibition of 4-methyllumbelliferone release by spectrophotometry,39. Inhibition of Bacteroides thetaiotaomicron beta-mannosidase 2A W395A mutant expressed in Escherichia coli assessed as inhibition of 4-methyllumbelliferone release by spectrophotometry,40. Inhibition of Bacteroides thetaiotaomicron beta-mannosidase 2A W198G mutant expressed in Escherichia coli assessed as inhibition of 4-methyllumbelliferone release by spectrophotometry,41. Inhibition of Bacteroides thetaiotaomicron beta-mannosidase 2A Y537A mutant expressed in Escherichia coli assessed as inhibition of 4-methyllumbelliferone release by spectrophotometry,42. Inhibition of Bacteroides thetaiotaomicron beta-mannosidase 2A Q646A mutant expressed in Escherichia coli assessed as inhibition of 4-methyllumbelliferone release by spectrophotometry,43. Inhibition of wild type Bacteroides thetaiotaomicron beta-mannosidase 2A expressed in Escherichia coli assessed as inhibition of 4-methyllumbelliferone release by spectrophotometry,44. Inhibition of wild type Bacteroides thetaiotaomicron beta-mannosidase 2A expressed in Escherichia coli BL21 (DE3) at 37 degC and Ph 5.6 by 2,4-dinitrophenolate release assay,45. Inhibition of Thermotoga maritima Beta-glucosidase GH1,46. Concentration of compound inhibiting alpha-Mannosidase isolated from Jack bean,47. Inhibition of alpha-Mannosidase isolated from almond,48. Binding affinity towards alpha-Mannosidase isolated from Jack bean,49. Binding affinity against alpha-Mannosidase isolated from Jack bean,50. Binding affinity towards alpha-Mannosidase isolated from Almond,51. Binding affinity towards alpha-Mannosidase isolated from Almond,52. Inhibitory activity towards Alpha-mannosidase from Jack bean,53. Inhibitory activity towards Alpha-mannosidase from Almond,54. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase GH92 alpha-mannosidase 4092 assessed as mannose release after 16 hrs by HPLC,55. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase GH92 alpha-mannosidase 4073 assessed as mannose release after 16 hrs by HPLC,56. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase GH92 alpha-mannosidase 3994 assessed as mannose release after 16 hrs by HPLC,57. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase GH92 alpha-mannosidase 3991 assessed as mannose release after 16 hrs by HPLC,58. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase GH92 alpha-mannosidase 3990 assessed as mannose release after 16 hrs by HPLC,59. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase GH92 alpha-mannosidase 3965 assessed as mannose release after 16 hrs by HPLC,60. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase GH92 alpha-mannosidase 3963 assessed as mannose release after 16 hrs by HPLC,61. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase GH92 alpha-mannosidase 3962 assessed as mannose release after 16 hrs by HPLC,62. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase GH92 alpha-mannosidase 3858 assessed as mannose release after 16 hrs by HPLC,63. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase GH92 alpha-mannosidase 3784 assessed as mannose release after 16 hrs by HPLC,64. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase GH92 alpha-mannosidase 3773 assessed as mannose release after 16 hrs by HPLC,65. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase GH92 alpha-mannosidase 3530 assessed as mannose release after 16 hrs by HPLC,66. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase GH92 alpha-mannosidase 1769 assessed as mannose release after 16 hrs by HPLC,67. Inhibitory activity towards Alpha-glucosidase from Rhizopus mold (amyloglucosidase),68. Inhibitory activity towards Alpha-glucosidase from Aspergillus niger (amyloglucosidase),69. Inhibition of drosophila golgi alpha-mannosidase 2,70. Inhibition of jack bean alpha-mannosidase,71. Inhibition of almond alpha-mannosidase assessed as p-nitrophenylglycoside substrate hydrolysis,72. Inhibition of jack bean alpha-mannosidase assessed as p-nitrophenylglycoside substrate hydrolysis,73. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 4093 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,74. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 4092 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,75. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 4073 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,76. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3994 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,77. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3991 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,78. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3990 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,79. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3965 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,80. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3963 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,81. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3962 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,82. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3858 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,83. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3784 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,84. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3130 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,85. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 2948 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,86. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 2199 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,87. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 1878 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,88. Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 1032 assessed as reduction of mannose release using 4NP-mannopyranoside substrate,89. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3990 E533A mutant assessed as as mannose release after 16 hrs by HPLC relative to wild type enzyme,90. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 2199 D648N mutant assessed as as mannose release after 16 hrs by HPLC relative to wild type enzyme,91. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 2199 D648A mutant assessed as as mannose release after 16 hrs by HPLC relative to wild type enzyme,92. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 2199 E537Q mutant assessed as as mannose release after 16 hrs by HPLC relative to wild type enzyme,93. Activity of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 2199 E537A mutant assessed as as mannose release after 16 hrs by HPLC relative to wild type enzyme,94. Activity of Bacteroides thetaiotaomicron GH
ACTIVITY	Substance BioActivity: 1 Tested Substance BioActivity: 2 Tested Substance BioActivity: 1 Active, 2 Tested Substance BioActivity: 1 Active, 1 Activity <= 1 µM, 1 Tested Substance BioActivity: 1 Active, 1 Tested Substance BioActivity: 2 Tested Substance BioActivity: 1 Active, 2 Tested Substance BioActivity: 6 Active, 4 Activity <= 1 µM, 6 Tested Substance BioActivity: 1 Active, 2 Tested Substance BioActivity: 2 Active, 1 Activity <= 1 µM, 4 Tested Substance BioActivity: 1 Active, 1 Activity <= 1 µM, 1 Tested Substance BioActivity: 1 Active, 1 Tested Substance BioActivity: 2 Active, 1 Activity <= 1 µM, 3 Tested Substance BioActivity: 2 Active, 1 Activity <= 1 µM, 7 Tested Substance BioActivity: 1 Tested Substance BioActivity: 2 Tested Substance BioActivity: 2 Active, 2 Tested Substance BioActivity: 1 Tested Substance BioActivity: 2 Active, 1 Activity <= 1 µM, 3 Tested Substance BioActivity: 2 Tested Substance BioActivity: 3 Tested Substance BioActivity: 1 Active, 6 Tested Substance