Detailed description page of Selected OV_ID


OV_859 details
Primary information
OV_IDOV_859
Virus Name Measles virus
StrainMV-Edm
Virus typeRNA
Virus familyParamyxoviridae
Modification in virus genomeRecombinant expressing a peptide
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomevirus expressing a marker peptide (MV-hCEA)
Source of cell lineNatural
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismFemale athymic mouse xenograft model for SKOV3 cell line
In-vivo virus concentration10⁷pfu/ml
In-vivo toxicityNA
In-vivo resultMedian survival time increased by >80 days
Mode of deliveryintraperitonial
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID12183422