| Primary information |
|---|
| OV_ID | OV_859 |
| Virus Name | Measles virus |
| Strain | MV-Edm |
| Virus type | RNA |
| Virus family | Paramyxoviridae |
| Modification in virus genome | Recombinant expressing a peptide |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | virus expressing a marker peptide (MV-hCEA) |
| Source of cell line | Natural |
| Origin of cell line | NA |
| Cell line | NA |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | NA |
| In-vitro virus concentration | NA |
| In-vitro result | NA |
| Model organism | Female athymic mouse xenograft model for SKOV3 cell line |
| In-vivo virus concentration | 10â·pfu/ml |
| In-vivo toxicity | NA |
| In-vivo result | Median survival time increased by >80 days |
| Mode of delivery | intraperitonial |
| Pathway induction | NA |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 12183422 |