Detailed description page of Selected OV_ID


OV_840 details
Primary information
OV_IDOV_840
Virus Name Herpes simplex virus
StrainHSV-G207
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeDeletion mutant of both copies of gamma 34.5 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismAthymic rat xenograft model for HCT8 cell line
In-vivo virus concentration1 × 10⁷ pfu
In-vivo toxicityNA
In-vivo result4 xenograft model shows complete reduction and 4 shows partial reduction (complete reduction)
Mode of deliveryDirect injection
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID10428757