Detailed description page of Selected OV_ID


OV_835 details
Primary information
OV_IDOV_835
Virus Name Herpes simplex virus
StrainHSV-G207
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeDeletion mutant of both copies of gamma 34.5 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNatural
Origin of cell linecolorectal cancer cell line
Cell lineC86
Concentration of cell line3
In-vitro toxicityNA
AssayBeta galacosidase colorimetric assay
In-vitro virus concentration0.1 MOI
In-vitro result76% cancer cell killing
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID10428757