Detailed description page of Selected OV_ID


OV_726 details
Primary information
OV_IDOV_726
Virus Name Avian influenza A virus
StrainH7N3 NS1-77
Virus typeRNA
Virus familyOrthomyxoviridae
Modification in virus genomeMutations were introduced within the IAV NS1 gene to create a truncated protein of 77 aa (NS1-77)
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismSCID-B17 female mice inoculated subcutaneously in the right flank with 100 μl of 5 × 10⁶ BxPC-3Luc cells
In-vivo virus concentration1 × 10⁵ PFU
In-vivo toxicityNA
In-vivo result%volume change is 90 as compared to control 340 after 23 days
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID27417501