Detailed description page of Selected OV_ID


OV_5882 details
Primary information
OV_IDOV_5882
Virus Name Herpes simplex virus
StrainMutant
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeDeletion mutant for Gamma 34.5 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeVirus expressing vasculostatin peptide
Source of cell lineATCC
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismAthymic mice xenograft for U87DeltaEGFR
In-vivo virus concentration1 ×10⁵ pfu
In-vivo toxicityNA
In-vivo resultSurvival time increased
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMIDUS8450106