Detailed description page of Selected OV_ID


OV_5585 details
Primary information
OV_IDOV_5585
Virus Name Reovirus
StrainReovirus strain T3D
Virus typeRNA
Virus familyReoviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineMurine fibroblast cell line
Cell lineTHC-11
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismSCID mice isograft for THC-11 (4.8 ×10⁵)
In-vivo virus concentration1 ×10⁷ pfu
In-vivo toxicityNA
In-vivo resultReduction in tumor volume 228mg compared to control 1523 mg after 3 weeks
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMIDUS7374752