Primary information |
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OV_ID | OV_5534 |
Virus Name | Herpes simplex virus |
Strain | G207-2 |
Virus type | DNA |
Virus family | Herpesviridae |
Modification in virus genome | Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | ATCC |
Origin of cell line | Human glioma cell line |
Cell line | U-87 MG |
Concentration of cell line | 0 |
In-vitro toxicity | NA |
Assay | Trypan blue cell exclusion assay |
In-vitro virus concentration | 0.01 MOI |
In-vitro result | 5% cell survival after day 5 |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | NA |
Immunogenic effect | NA |
Clinical trial | NA |
PMID | US6139834 |