Detailed description page of Selected OV_ID


OV_5386 details
Primary information
OV_IDOV_5386
Virus Name Maraba virus
StrainMG1
Virus typeRNA
Virus familyRhabdoviridae
Modification in virus genomeNone
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with 2mg/kg micromolar palcitaxel for 48 hours
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismC57/Bl6 mice isograft for 1 × 10⁶ EO771 cells
In-vivo virus concentrationReduction in tumor volume to 100 cubic mm compared to control 1200 cubic mm after 30 days and increase in survival time to 70 days compared to 32 days control
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryIntratumoral
Pathway inductionInduction of apoptosis
Immunogenic effectLevel of IFN beta production does not effected by combination
Clinical trialIn clinical trial for various cancer cell line
PMID27503504