Detailed description page of Selected OV_ID


OV_5350 details
Primary information
OV_IDOV_5350
Virus Name Adenovirus
StrainYDC002
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeVirus having insertion mutant for relaxin gene
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with gemcitabine 0.05 micromoar
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman pancreatic cancer cell line
Cell lineMIAPaCa-2
Concentration of cell line5
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration2 MOI
In-vitro result30% cells remain viable after 72 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus induced apoptosis
Immunogenic effectNA
Clinical trialNA
PMID28315430