Detailed description page of Selected OV_ID


OV_5331 details
Primary information
OV_IDOV_5331
Virus Name Adenovirus
StrainZD55-IL18
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomevirus having insertion of IL18 gene
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with DTIC 200 microgram per ml
Immune gene induction in virus genomeVirus expressing IL18 gene
Source of cell lineNA
Origin of cell lineHuman skin melanoma cell line
Cell lineA375
Concentration of cell line0
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration10 MOI
In-vitro result30% cell viability on day 4
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus induced apoptosis as measured by TUNEL assay
Immunogenic effectNA
Clinical trialNA
PMID27895465