Detailed description page of Selected OV_ID


OV_5321 details
Primary information
OV_IDOV_5321
Virus Name Adenovirus
StrainZD55-IL18
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomevirus having insertion of IL18 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeVirus expressing IL18 gene
Source of cell lineNA
Origin of cell lineHuman skin melanoma cell line
Cell lineA375
Concentration of cell line0
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration10 MOI
In-vitro result78% cell viability on day 2
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus induced apoptosis as measured by TUNEL assay
Immunogenic effectNA
Clinical trialNA
PMID27895465