Detailed description page of Selected OV_ID


OV_5187 details
Primary information
OV_IDOV_5187
Virus Name Tanapoxvirus
StrainTPV-delta15Ldelta66R
Virus typeDNA
Virus familyPoxviridae
Modification in virus genomeDeletion mutant for 15L gene and tk 66R locus
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismAthymic nude mice CrlNU-Foxn1 xenograft for cellosaurus cell line 5 × 10⁶ cells
In-vivo virus concentration5 × 10⁶ pfu
In-vivo toxicityNA
In-vivo resultReduction in tumor growth 200 compared to 550 after 34 days
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID27738905