Detailed description page of Selected OV_ID


OV_4882 details
Primary information
OV_IDOV_4882
Virus Name Adenovirus
StrainAd-deltaB
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineJCRB gene bank japan
Origin of cell lineHuman hepatocellular carcinoma
Cell lineHuh-7
Concentration of cell line70
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration10 MOI
In-vitro result60% cell viability after 48 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionCombination therapy and alone promotes apoptosis
Immunogenic effectActivation of caspase-3 and 8 and upregulation of IFN-gamma
Clinical trialNA
PMID27154307