Detailed description page of Selected OV_ID


OV_4631 details
Primary information
OV_IDOV_4631
Virus Name Adenovirus
StrainAd5/3-delata 24
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeMutation in delta E3 and delta 24 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismFemale athymic nude mice xenograft for UPCI SCC 090 (2 × 10⁶)
In-vivo virus concentration3.5 × 10¹¹ pfu
In-vivo toxicityNA
In-vivo resultComplete ereduction in tumor volume after 30 days
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID27086483