Detailed description page of Selected OV_ID


OV_4114 details
Primary information
OV_IDOV_4114
Virus Name Adenovirus
StrainAd-CCL20-CD40L
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeAddition of CCL20 and CD40L gene near by TERT promoter
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomevirus expressing CCL20 chemokine gene
Source of cell lineATCC
Origin of cell lineHuman colon carcinoma cell line
Cell lineCaco-2
Concentration of cell line1
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration1 MOI
In-vitro result40% cell survival after 7 days
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID26208317