Detailed description page of Selected OV_ID


OV_3518 details
Primary information
OV_IDOV_3518
Virus Name Adenovirus
StrainAdenovirus ZD55-shMYCN
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeVirus expressing MYCN gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineLab own synthesized
Origin of cell lineHuman neuroblastoma cell line
Cell lineLA1-55n/Dox-R
Concentration of cell line2
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration10 MOI
In-vitro result50% cells remain viable after 6 days
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis as measured by TUNEL assay
Immunogenic effectNA
Clinical trialNA
PMID28711493