Primary information |
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OV_ID | OV_3360 |
Virus Name | Reovirus |
Strain | Recombinant reovirus T3L |
Virus type | RNA |
Virus family | Reoviridae |
Modification in virus genome | Substitution mutant in T3 gene |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | ATCC |
Origin of cell line | Human lung cancer cell line |
Cell line | H1437 |
Concentration of cell line | 1 |
In-vitro toxicity | NA |
Assay | Cell-titer-glo assay |
In-vitro virus concentration | 100 pfu |
In-vitro result | 85% cell viability after 24 hours |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | Induction of apoptosis |
Immunogenic effect | NA |
Clinical trial | NA |
PMID | 28587298 |