| Primary information |
|---|
| OV_ID | OV_2932 |
| Virus Name | Mumps virus |
| Strain | wild type |
| Virus type | RNA |
| Virus family | Paramyxoviridae |
| Modification in virus genome | None |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | Laboratory grown own culture |
| Origin of cell line | Leukemia cell line |
| Cell line | U937 |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | NA |
| In-vitro virus concentration | NA |
| In-vitro result | NA |
| Model organism | BALB/c nude mice xenograft for U937 |
| In-vivo virus concentration | 1 × 10ⵠpfu
|
| In-vivo toxicity | NA |
| In-vivo result | Tumor volume regressed to below 5 mm after 14 days |
| Mode of delivery | Intratumoral |
| Pathway induction | Induction of apoptosis by virus alone and in combination |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 25193462 |