Primary information |
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OV_ID | OV_2283 |
Virus Name | Vesicular stomatitis virus |
Strain | VSV-Delta-M51-GFP |
Virus type | RNA |
Virus family | Rhabdoviridae |
Modification in virus genome | Deletion of M51 gene and insertion of GFP gene |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | ATCC |
Origin of cell line | Pancreatic ductal adeonocarcinoma cell line |
Cell line | SU.86.86 |
Concentration of cell line | 80 |
In-vitro toxicity | NA |
Assay | MTT assay |
In-vitro virus concentration | 1 MOI |
In-vitro result | 4% cell survival after 5 days |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | NA |
Immunogenic effect | Downregulation of IFN-Gamma |
Clinical trial | NA |
PMID | 22238308 |