Detailed description page of Selected OV_ID


OV_2199 details
Primary information
OV_IDOV_2199
Virus Name Herpes simplex virus
StrainHSV-1-G47-delta
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeMutant for Gamma34.5, ICP6 and alpha47 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineDr. George SW Tsao Center, Hong Komg university
Origin of cell lineHuman nasopharyngeal carcinoma cell line
Cell lineNP69
Concentration of cell line1
In-vitro toxicityNA
AssayX-gal staining and MTT assay
In-vitro virus concentration0.01 MOI
In-vitro result95% cell survival after day 1
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID22059912