Detailed description page of Selected OV_ID


OV_2197 details
Primary information
OV_IDOV_2197
Virus Name Herpes simplex virus
StrainHSV-1-G47-delta
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeMutant for Gamma34.5, ICP6 and alpha47 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineHongkong university
Origin of cell lineHuman nasopharyngeal carcinoma cell line
Cell lineNPEC2/Bm1
Concentration of cell line1
In-vitro toxicityNA
AssayX-gal staining and MTT assay
In-vitro virus concentration0.1 MOI
In-vitro result10% cell survival after day 4
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID22059912