Detailed description page of Selected OV_ID


OV_1841 details
Primary information
OV_IDOV_1841
Virus Name Vesicular stomatitis virus
StrainMutant
Virus typeRNA
Virus familyRhabdoviridae
Modification in virus genomeVirus expressing GFP protein
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismC57BL/6 mic, injected for TRAMP-C2 cell line
In-vivo virus concentration2 × 10⁷ pfu
In-vivo toxicityNA
In-vivo resultReduction in tumor volume after 42 days
Mode of deliveryIntratumoral
Pathway inductionVirus induce apoptosis in cancer cells
Immunogenic effectNA
Clinical trialNA
PMID20172545