| Primary information |
|---|
| OV_ID | OV_1841 |
| Virus Name | Vesicular stomatitis virus |
| Strain | Mutant |
| Virus type | RNA |
| Virus family | Rhabdoviridae |
| Modification in virus genome | Virus expressing GFP protein |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | NA |
| Origin of cell line | NA |
| Cell line | NA |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | NA |
| In-vitro virus concentration | NA |
| In-vitro result | NA |
| Model organism | C57BL/6 mic, injected for TRAMP-C2 cell line |
| In-vivo virus concentration | 2 × 10ⷠpfu
|
| In-vivo toxicity | NA |
| In-vivo result | Reduction in tumor volume after 42 days |
| Mode of delivery | Intratumoral |
| Pathway induction | Virus induce apoptosis in cancer cells |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 20172545 |