Detailed description page of Selected OV_ID


OV_1680 details
Primary information
OV_IDOV_1680
Virus Name Measles virus
StrainMV-Edm strain
Virus typeRNA
Virus familyParamyxoviridae
Modification in virus genomeMV-NPL virus , addition of P, N and L gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineHuman renal cell carcinoma cell line
Cell lineA-498
Concentration of cell line2
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration0.1 MOI
In-vitro result60% cell survival after 96 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus induce apoptosis in cancer cells
Immunogenic effectInduce expression of IFN-gamma, an antiviral protein
Clinical trialNA
PMID20051938