Primary information |
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OV_ID | OV_1675 |
Virus Name | Measles virus |
Strain | MV-Edm strain |
Virus type | RNA |
Virus family | Paramyxoviridae |
Modification in virus genome | MV-P virus , addition of P gene |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | NA |
Origin of cell line | Human renal cell carcinoma cell line |
Cell line | A-498 |
Concentration of cell line | 2 |
In-vitro toxicity | NA |
Assay | MTT assay |
In-vitro virus concentration | 0.1 MOI |
In-vitro result | 80% cell survival after 96 hours |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | Virus induce apoptosis in cancer cells |
Immunogenic effect | Induce expression of IFN-gamma, an antiviral protein |
Clinical trial | NA |
PMID | 20051938 |