Detailed description page of Selected OV_ID


OV_1148 details
Primary information
OV_IDOV_1148
Virus Name Herpes simplex virus
StrainMutant
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeMutant for gamma 34.5, lacZ and alpha 47 gene
Virus aloneNo
Virus in combination iwth drug/radiationVirus strain in combination with flutamide
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBALB/c nude mice xenograft for Human prostatic cancer HONDA
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultSignificant reduction in tumor volume as compared to flutamide alone
Mode of deliverySubcutaneous
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID16278413