Detailed description page of Selected OV_ID


OV_1147 details
Primary information
OV_IDOV_1147
Virus Name Herpes simplex virus
StrainMutant
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeMutant for gamma 34.5, lacZ and alpha 47 gene
Virus aloneNo
Virus in combination iwth drug/radiationVirus strain in combination with androgen ablation therapy
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismC57BL/6 mice model isograft for TRAMP-C2 cell line
In-vivo virus concentration5 × 10⁶ pfu
In-vivo toxicityNA
In-vivo resultReduction in tumor volume as compared to castration
Mode of deliverySubcutaneous
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID16278413